GNH USA

Europe — EMA

Imazol Plus

GNH USA supplies Imazol Plus (Clotrimazole / Hexamidine diisetionate), an antifungal for tinea pedis, tinea corporis and candidiasis. Request a quote today.

Clotrimazole, Hexamidine Diisetionate

Request sourcing

1
Pack/s

What is Clotrimazole, Hexamidine Diisetionate?

Clotrimazole, the active ingredient in Imazol Plus, is an antifungal; Hexamidine diisetionate, also present, is an antiseptic presented as a topical formulation for skin use. It treats dermatophytosis, tinea pedis, tinea corporis and cutaneous candidiasis in adults and children and is suitable for over‑the‑counter use in many European markets.

GNH USA supplies Imazol Plus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches for global distribution.

What is Clotrimazole, Hexamidine Diisetionate used for?

Imazol Plus combines an antifungal and antiseptic to treat superficial fungal infections of the skin.

- Dermatophytosis: reduces fungal growth and relieves itching and scaling. - Tinea pedis: clears foot‑area infection and diminishes redness. - Tinea corporis: eliminates body‑area ringworm lesions. - Cutaneous candidiasis: eradicates yeast overgrowth on the skin.

What are the side effects of Clotrimazole, Hexamidine Diisetionate?

Topical application of Imazol Plus may cause local skin reactions, ranging from mild irritation to rare severe hypersensitivity.

Common Side Effects: - Burning sensation: transient discomfort at the application site. - Itching: mild pruritus may occur. - Redness: localized erythema. - Dryness: skin may feel less moist. - Irritation: mild stinging or tingling. - Contact dermatitis: mild allergic skin response.

Serious or Rare Side Effects: - Severe allergic reaction: swelling, hives, or difficulty breathing. - Blistering or ulceration: extensive skin breakdown. - Stevens‑Johnson syndrome: rare but severe mucocutaneous eruption. - Systemic toxicity: unlikely but possible with extensive use. - Persistent rash: may indicate secondary infection. - Necrotizing fasciitis: extremely rare, requires immediate medical attention.

What precautions apply to Clotrimazole, Hexamidine Diisetionate?

Before using Imazol Plus, consider the following safety measures.

- Avoid application on broken skin: may increase irritation. - Do not use on mucous membranes: product not intended for oral or ocular use. - Limit use to recommended duration: prolonged use may lead to resistance. - Discontinue if severe irritation occurs: seek medical advice. - Pregnancy and lactation: consult a healthcare professional before use. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Clotrimazole, Hexamidine Diisetionate interact with?

Imazol Plus may interact with other topical agents; review the following categories.

Major Interactions (Avoid): - Concurrent use with other topical azole antifungals: risk of additive irritation. - Use with topical corticosteroids: may mask infection signs. - Systemic antifungal therapy: may increase systemic absorption (rare).

Moderate Interactions (Monitor Closely): - Co‑application with alcohol‑based moisturizers: may enhance burning. - Use with adhesive dressings: may trap product and increase irritation. - Concurrent use of other antiseptic agents: may cause cumulative skin dryness.

Frequently asked questions

What conditions is Imazol Plus used for?+
Imazol Plus is indicated for the topical treatment of superficial fungal skin infections such as dermatophytosis, tinea pedis (athlete’s foot), tinea corporis (ringworm of the body) and cutaneous candidiasis caused by yeast overgrowth.
How does clotrimazole work in Imazol Plus?+
Clotrimazole inhibits the fungal enzyme lanosterol 14‑α‑demethylase, which blocks the synthesis of ergosterol, an essential component of fungal cell membranes, leading to loss of membrane integrity and fungal cell death.
What is the usual dose of Imazol Plus?+
The dosage of Imazol Plus is determined by the prescribing healthcare professional based on the specific infection, severity, patient age and treatment duration. Patients should follow the prescriber’s instructions and the product label.
Is Imazol Plus safe during pregnancy or breastfeeding?+
Safety data for Imazol Plus in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.
How do I order Imazol Plus from GNH USA?+
To order Imazol Plus, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and required import documentation.
How does Imazol Plus compare with other topical antifungals?+
Imazol Plus combines clotrimazole, a widely used azole antifungal, with hexamidine diisetionate, an antiseptic that adds antibacterial activity. This dual action can be advantageous over single‑agent antifungals when mixed bacterial‑fungal skin infections are suspected.
What are the storage requirements for Imazol Plus?+
Store Imazol Plus at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, excessive heat and direct sunlight to maintain stability and efficacy.
How is Imazol Plus applied?+
Imazol Plus is applied topically to the affected skin area. Clean and dry the area before use, then spread a thin layer of the product as directed by the prescriber, typically twice daily, and wash hands after application.
What are the most serious risks associated with Imazol Plus?+
Serious risks, although rare, include severe allergic reactions such as swelling, hives, or difficulty breathing, and severe skin reactions like Stevens‑Johnson syndrome or extensive blistering. Immediate medical attention is required if these symptoms occur.
Who should not use Imazol Plus?+
Imazol Plus should not be used by individuals with known hypersensitivity to clotrimazole, hexamidine diisetionate or any excipients in the formulation. It is also contraindicated on broken skin, mucous membranes, or in patients with severe liver disease without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Clotrimazole, Hexamidine Diisetionate
Route
Cutaneous Use
Manufacturer
Laboratoires Bailleul S.A.
Origin
EU

Related products