GNH USA

Europe — EMA

Imazol Plus

GNH USA supplies Imazol Plus (Clotrimazole, Hexamidine), a topical antifungal and antiseptic for tinea corporis, tinea pedis and cutaneous candidiasis.

Clotrimazole, Hexamidine Diisetionate

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What is Clotrimazole, Hexamidine Diisetionate?

Clotrimazole, the active ingredient in Imazol Plus, is an antifungal presented as a topical preparation for skin use. It treats superficial fungal infections such as tinea corporis, tinea pedis and cutaneous candidiasis in both adults and children, often in combination with the antiseptic Hexamidine diisetionate to broaden antimicrobial coverage.

GNH USA supplies Imazol Plus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Clotrimazole, Hexamidine Diisetionate used for?

Imazol Plus is a topical antifungal/antiseptic used for common superficial skin infections.

- Tinea corporis: reduces fungal growth and clears the ring‑shaped rash on the body. - Tinea pedis: alleviates itching and eliminates the dermatophyte causing athlete's foot. - Cutaneous candidiasis: eradicates Candida species from moist skin areas, promoting healing.

What are the side effects of Clotrimazole, Hexamidine Diisetionate?

Topical application of Imazol Plus may cause local reactions.

Common Side Effects: - Mild burning or stinging at the application site. - Redness or erythema. - Pruritus or itching. - Dryness or flaking of the skin. - Minor irritation or rash.

Serious or Rare Side Effects: - Severe allergic dermatitis with swelling. - Contact urticaria or hives. - Bullous skin reactions. - Secondary bacterial infection of the treated area. - Persistent or worsening irritation requiring medical review.

What precautions apply to Clotrimazole, Hexamidine Diisetionate?

Before using Imazol Plus, consider the following precautions.

- Allergic History: avoid if known hypersensitivity to clotrimazole, hexamidine or formulation excipients. - Open Wounds: do not apply on extensive open wounds or mucous membranes. - Pediatric Use: consult a healthcare professional before use on infants or young children. - Concomitant Skin Products: avoid using other topical medications on the same area unless directed. - Pregnancy and Breastfeeding: discuss with a clinician as safety data are limited. - Store at room temperature: keep in original container, protect from moisture and direct sunlight.

What does Clotrimazole, Hexamidine Diisetionate interact with?

Imazol Plus may interact with other topical agents or systemic drugs.

Major Interactions (Avoid): - Concurrent use with other potent topical antifungals (e.g., terbinafine) may increase irritation risk. - Application over areas treated with corticosteroids can mask infection signs.

Moderate Interactions (Monitor Closely): - Use with occlusive dressings may enhance systemic absorption. - Systemic antifungal therapy (e.g., oral azoles) may potentiate local effects. - Antiseptic soaps containing chlorhexidine may reduce efficacy of the product.

Frequently asked questions

What conditions is Imazol Plus used for?+
Imazol Plus is a topical preparation indicated for superficial fungal skin infections such as tinea corporis (ringworm), tinea pedis (athlete’s foot) and cutaneous candidiasis. It combines an antifungal and an antiseptic to treat and prevent secondary bacterial involvement.
How does clotrimazole work in Imazol Plus?+
Clotrimazole blocks the enzyme responsible for synthesising ergosterol, a key component of fungal cell membranes. Without ergosterol, the membrane becomes permeable, leading to fungal cell death. Hexamidine diisetionate adds antiseptic activity by disrupting microbial membranes.
What is the usual dose of Imazol Plus?+
The dosage regimen for Imazol Plus is determined by the prescribing clinician based on the infection type, severity and patient age. Typically, a thin layer is applied to the affected skin once or twice daily for the period advised by the healthcare professional.
Is Imazol Plus safe during pregnancy or breastfeeding?+
Safety data for Imazol Plus in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy or breastfeeding should discuss potential risks with their healthcare provider before using the product.
How do I order Imazol Plus from GNH USA?+
To order Imazol Plus, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Imazol Plus compare with other topical antifungals?+
Imazol Plus combines clotrimazole with hexamidine, offering both antifungal and antiseptic actions. Compared with single‑agent products such as terbinafine or miconazole, it may provide broader coverage against bacterial colonisation, though clinical choice depends on infection type, patient tolerance and physician preference.
What are the storage requirements for Imazol Plus?+
Store Imazol Plus at room temperature, below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging until use.
How is Imazol Plus applied?+
Imazol Plus is applied topically to clean, dry skin. A thin film should be spread over the affected area and surrounding margin, usually once or twice daily as directed by a healthcare professional. Hands should be washed after application.
What are the most serious risks associated with Imazol Plus?+
Serious risks, though rare, include severe allergic reactions such as contact dermatitis, urticaria, or bullous skin eruptions. If signs of a serious skin reaction or systemic symptoms develop, discontinue use and seek medical attention promptly.
Who should not use Imazol Plus?+
Individuals with a known hypersensitivity to clotrimazole, hexamidine diisetionate or any excipients in the formulation should avoid Imazol Plus. It is also not recommended for use on extensive open wounds, mucous membranes or in patients where a clinician advises against topical antifungal therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Clotrimazole, Hexamidine Diisetionate
Route
Cutaneous Use
Manufacturer
Laboratoires Bailleul S.A.
Origin
EU

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