Imazol Plus (Clotrimazole, Hexamidine Diisetionate)

Clotrimazole and Hexamidine diisetionate, the active ingredients in Imazol Plus, are antifungal and antiseptic agents presented as a topical formulation for skin use. They are intended for external application to treat fungal and superficial bacterial skin conditions in adults and children. GNH USA supplies Imazol Plus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Imazol Plus combines antifungal and antiseptic activity to address common superficial skin infections. - Dermatophyte skin infections (e.g., tinea pedis, tinea cruris): reduces fungal growth and relieves itching and scaling. - Candidal skin infections: eradicates superficial Candida species and promotes healing of affected areas. - Superficial bacterial skin infections: provides antiseptic action that limits bacterial colonisation and supports recovery.

Imazol Plus is generally well tolerated, but local skin reactions can occur.

Common Side Effects: - Mild burning or stinging at the application site - Itching or mild pruritus - Redness or erythema - Dryness or flaking of the skin - Slight swelling or edema - Contact dermatitis in sensitive individuals

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with difficulty breathing - Swelling of the face, lips, or tongue - Extensive blistering or bullous dermatitis - Necrotic skin lesions or ulceration - Systemic hypersensitivity reactions such as fever or malaise - Persistent or worsening irritation requiring medical attention

Before using Imazol Plus, consider the following safety measures. - Avoid use on broken skin: limit application to intact epidermis unless directed by a clinician. - Do not apply to mucous membranes: keep away from eyes, mouth and genital mucosa. - Discontinue if severe irritation occurs: seek medical advice promptly. - Pregnancy and lactation: consult a healthcare professional before use. - Concurrent use with other topical antifungals: assess for additive irritation. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Imazol Plus may interact with other topical or systemic agents.

Major Interactions (Avoid): - Concurrent use with systemic antifungals: may increase systemic exposure and risk of toxicity. - Use with topical corticosteroids: can reduce antifungal efficacy. - Co‑application with other antiseptic creams containing chlorhexidine: heightened risk of skin irritation.

Moderate Interactions (Monitor Closely): - Use with other skin irritants (e.g., retinoids or alpha‑hydroxy acids): monitor for increased local irritation. - Combination with occlusive dressings: may enhance absorption, watch for local adverse reactions.