Europe — EMA
Imazol Plus
GNH USA supplies Imazol Plus (Clotrimazole/Hexamidine), a dermatological anti‑infective for fungal and mixed skin infections. Request a quote for supply.
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What is Clotrimazole, Hexamidine Diisetionate?
Clotrimazole and Hexamidine diisetionate, the active ingredients in Imazol Plus, are antifungal and antiseptic agents presented as a topical formulation for skin use. They are used to treat superficial fungal and mixed fungal‑bacterial skin infections in adults and children when appropriate. GNH USA supplies Imazol Plus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Clotrimazole, Hexamidine Diisetionate used for?
Imazol Plus acts on superficial dermatological infections caused by fungi and mixed microbial flora. - Dermatophyte infections (e.g., tinea corporis, tinea cruris): Reduces fungal growth and alleviates lesion symptoms. - Candidal skin infections: Inhibits Candida proliferation and promotes healing of affected areas. - Mixed fungal‑bacterial skin infections: Provides combined antifungal and antiseptic activity to control both pathogen types. - Superficial cutaneous mycoses: Helps clear infection and prevent recurrence when applied as directed.
What are the side effects of Clotrimazole, Hexamidine Diisetionate?
Imazol Plus may cause local skin reactions, most of which are mild and self‑limiting.
Common Side Effects: - Mild burning or stinging at the application site - Itching or pruritus - Redness or erythema - Dryness or flaking of the skin - Slight swelling or edema - Contact dermatitis
Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) - Extensive skin ulceration or necrosis - Bullous or vesicular dermatitis - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Systemic hypersensitivity with fever or malaise - Severe edema or angioedema
What precautions apply to Clotrimazole, Hexamidine Diisetionate?
Before using Imazol Plus, consider the following precautions. - Pregnancy: Safety not established; use only if benefits outweigh potential risks. - Breastfeeding: Unknown safety; evaluate risk versus benefit with a healthcare professional. - Age: Not recommended for children under 2 years unless specifically prescribed. - Skin condition: Avoid application on extensive damaged skin, mucous membranes, or severe burns. - Concomitant topical agents: Do not combine with other irritant or sensitizing products without medical advice. - Store at ambient temperature: Keep in original container, protect from moisture and direct sunlight.
What does Clotrimazole, Hexamidine Diisetionate interact with?
Imazol Plus may interact with other topical or systemic agents.
Major Interactions (Avoid): - Concurrent use with other azole antifungal creams: May increase local irritation. - Combination with systemic antifungals metabolized by CYP450 enzymes: Potential additive toxicity. - Co‑application with potent topical corticosteroids: May mask infection signs and delay healing.
Moderate Interactions (Monitor Closely): - Use with skin sensitizers or allergens: Monitor for heightened allergic responses. - Application under occlusive dressings: May increase drug absorption and local irritation.
Frequently asked questions
What is Imazol Plus used for?+
How does clotrimazole work?+
What is the usual dose?+
Is Imazol Plus safe in pregnancy or breastfeeding?+
How do I order Imazol Plus from GNH USA?+
How does Imazol Plus compare with other antifungal creams?+
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Product details
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