Oftan Dexa-Chlora (Chloramphenicol, Dexamethasone)

Chloramphenicol and dexamethasone, the active ingredients in Oftan Dexa-Chlora, are an antibiotic and a corticosteroid presented as an ophthalmic preparation for ocular use. They treat bacterial conjunctivitis, ocular inflammation and are used for post‑operative prophylaxis in patients who need topical therapy.

GNH USA supplies Oftan Dexa-Chlora as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Oftan Dexa‑Chlora combines an antibacterial and anti‑inflammatory agent to address ocular infections and inflammation.

- Bacterial conjunctivitis: reduces bacterial load and resolves redness and discharge. - Ocular inflammation: suppresses inflammatory cytokines, decreasing swelling and pain. - Post‑operative prophylaxis: prevents infection and inflammation after eye surgery.

Oftan Dexa‑Chlora may cause local ocular reactions and, rarely, systemic adverse events.

Common Side Effects: - Stinging or burning sensation upon instillation. - Transient blurred vision. - Mild ocular irritation or redness. - Increased intra‑ocular pressure with prolonged use.

Serious or Rare Side Effects: - Corneal ulceration or secondary infection. - Cataract formation with long‑term corticosteroid exposure. - Systemic bone‑marrow suppression from chloramphenicol absorption. - Glaucoma development due to sustained pressure rise. - Allergic hypersensitivity reactions, including angioedema.

Before using Oftan Dexa‑Chlora, consider the following safety measures.

- Pregnancy: consult a physician; limited safety data are available. - Breastfeeding: weigh potential risks to the infant before use. - Children: use only under medical supervision and for approved indications. - Contact lens wearers: avoid use or remove lenses before instillation. - Prolonged therapy: monitor intra‑ocular pressure and signs of secondary infection. - Store at room temperature: keep in original container, protect from light and moisture.

Oftan Dexa‑Chlora can interact with systemic and ocular medications.

Major Interactions (Avoid): - Systemic chloramphenicol: additive risk of bone‑marrow suppression. - Systemic corticosteroids: increased systemic glucocorticoid effects. - Live vaccines: potential immunosuppression may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely): - Topical non‑steroidal anti‑inflammatory eye drops: may increase ocular irritation. - Antifungal eye drops: possible reduced antifungal activity. - Contact lens solutions: may affect drug stability or cause precipitation.