Europe — EMA
Noskapin Orifarm Healthcare (Noscapine Hydrochloride Monohydrate)
GNH USA supplies Noskapin Orifarm Healthcare (Noscapine), a antitussive for dry and non‑productive cough. Request a quote for global supply to hospitals.
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What is Noscapine Hydrochloride Monohydrate?
Noscapine Hydrochloride Monohydrate, the active ingredient in Noskapin Orifarm Healthcare, is an antitussive presented as an oral formulation for oral use. It is used to suppress dry and non‑productive coughs in adults and children as directed by a healthcare professional.
GNH USA supplies Noskapin Orifarm Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Noscapine Hydrochloride Monohydrate used for?
Noscapine is a non‑opioid antitussive that acts on the central cough centre to reduce cough reflex.
- Dry cough: decreases the frequency and intensity of coughing episodes. - Non‑productive cough: suppresses cough without producing sputum. - Cough due to upper‑respiratory irritation: provides symptomatic relief of irritation‑induced coughing.
What are the side effects of Noscapine Hydrochloride Monohydrate?
Common Side Effects: - Nausea: mild gastrointestinal upset may occur. - Dizziness: transient light‑headedness reported by some users. - Drowsiness: occasional sedation, especially at higher doses. - Headache: mild headache may be experienced.
Serious or Rare Side Effects: - Allergic reactions: rash, itching, or anaphylaxis in hypersensitive individuals. - Severe skin reactions: rare cases of Stevens‑Johnson syndrome. - Hepatic dysfunction: elevated liver enzymes reported rarely. - Neutropenia: uncommon reduction in white blood cell count. - Respiratory depression: extremely rare, usually with concomitant CNS depressants.
What precautions apply to Noscapine Hydrochloride Monohydrate?
Before using Noskapin Orifarm Healthcare, consider the following precautions.
- Pediatric use: follow prescriber guidance for children, as dosing may differ. - Hypersensitivity: avoid if known allergy to noscapine or excipients. - Hepatic impairment: use with caution in patients with liver disease. - Concomitant cough suppressants: do not combine with other antitussives without medical advice. - Sedation risk: avoid operating machinery if drowsiness occurs. - Store below 25°C: keep in the original pack, protect from moisture.
What does Noscapine Hydrochloride Monohydrate interact with?
Noskapin Orifarm Healthcare may interact with other medicines; review the following.
Major Interactions (Avoid): - Central nervous system depressants: may increase sedation and respiratory depression. - Other antitussives: combined use can lead to excessive cough suppression. - Opioid cough suppressants: additive CNS effects should be avoided.
Moderate Interactions (Monitor Closely): - Alcohol: can enhance drowsiness and dizziness. - Antihistamines: may increase sedation when taken together. - CYP450 inhibitors: potential alteration of noscapine metabolism, requiring monitoring.
Frequently asked questions
What is Noskapin Orifarm Healthcare used for?+
How does noscapine work to suppress cough?+
What is the usual dose of Noskapin Orifarm Healthcare?+
Is Noskapin Orifarm Healthcare safe during pregnancy or breastfeeding?+
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