Nosca-Méréprine (Noscapine Hydrochloride Monohydrate)

Noscapine hydrochloride monohydrate, the active ingredient in Nosca-Méréprine, is an antitussive presented as an oral dosage form for oral use. It suppresses non‑productive cough in adults and children.\n\nGNH India supplies Nosca-Méréprine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nosca-Méréprine acts as a central cough suppressant and is used for conditions involving irritating cough reflexes.\n\nNon‑productive cough: reduces cough frequency and provides symptomatic relief.\nAcute cough due to upper respiratory infection: helps suppress cough episodes during the early phase of infection.\nChronic non‑productive cough in adults: aids in cough control when other causes have been excluded.

Common Side Effects:\n- Drowsiness: mild sleepiness may occur after oral administration.\n- Nausea: occasional stomach upset reported.\n- Dizziness: transient light‑headedness in some patients.\n- Dry mouth: reduced salivation leading to a dry sensation.\n\nSerious or Rare Side Effects:\n- Allergic reactions: rash, itching, or angioedema requiring medical attention.\n- Severe skin reactions: rare cases of Stevens‑Johnson syndrome.\n- Hepatic enzyme elevation: occasional abnormal liver function tests observed.

Before using Nosca-Méréprine, consider the following precautions.\n\nPregnancy: safety not established; use only if clearly needed.\nBreastfeeding: unknown safety; weigh potential risks and benefits.\nRenal impairment: use with caution and monitor renal function.\nDrug interactions: review all concomitant medications for possible interactions.\nStore at ambient temperature (below 25°C): keep in the original pack, protect from moisture.

Nosca-Méréprine may interact with other substances that affect the central nervous system.\n\nMajor Interactions (Avoid):\n- Concurrent use with potent CNS depressants: may enhance sedation and respiratory depression.\n- Combination with MAO inhibitors: not recommended due to unknown interaction risk.\n\nModerate Interactions (Monitor Closely):\n- Antihistamines: may increase antitussive effect and cause excess drowsiness.\n- Opioid cough suppressants: additive cough‑suppressing effect could lead to over‑suppression.\n- Alcohol: may potentiate drowsiness and dizziness.