GNH USA

Europe — EMA

Natterman Noscasan (Noscapine Hydrochloride Monohydrate)

GNH USA supplies Natterman Noscasan (Noscapine Hydrochloride), a centrally acting antitussive for acute and chronic cough. Request a quote for global supply.

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What is Noscapine Hydrochloride Monohydrate?

Noscapine Hydrochloride Monohydrate, the active ingredient in Natterman Noscasan, is an antitussive (alkaloid) presented as an oral dosage form for oral use. It is employed to suppress cough in adults and children when a non‑opioid option is preferred.

GNH USA supplies Natterman Noscasan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides batch‑tested product for global distribution.

What is Noscapine Hydrochloride Monohydrate used for?

Natterman Noscasan, a centrally acting antitussive, is used to manage cough associated with various respiratory conditions.

Acute cough: provides symptomatic relief of cough caused by common colds or upper respiratory infections. Chronic non‑productive cough: helps reduce persistent dry cough when other treatments are ineffective. Cough due to bronchitis: suppresses irritating cough reflex in acute bronchitis.

What are the side effects of Noscapine Hydrochloride Monohydrate?

Adverse reactions to Natterman Noscasan are generally mild, but some patients may experience more serious events.

Common Side Effects: - Nausea: mild stomach upset. - Dizziness: transient light‑headedness. - Drowsiness: increased sleepiness. - Headache: mild to moderate.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling of face or throat. - Hepatic dysfunction: elevated liver enzymes or jaundice. - Neutropenia: reduced white blood cell count, increasing infection risk.

What precautions apply to Noscapine Hydrochloride Monohydrate?

When prescribing Natterman Noscasan, clinicians should consider several safety aspects.

Pregnancy: safety not established; avoid unless clearly needed. Breastfeeding: caution as drug may be excreted in milk. Renal impairment: monitor and adjust if necessary. Concomitant CNS depressants: may enhance sedation. Known hypersensitivity: contraindicated in patients with allergy to noscapine. Store at ambient temperature: keep in original container, protect from moisture and light.

What does Noscapine Hydrochloride Monohydrate interact with?

Natterman Noscasan may interact with other medicines; awareness of potential interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - CNS depressants: additive sedation and respiratory depression. - MAO inhibitors: risk of enhanced central effects. - Antihistamines: increased drowsiness.

Moderate Interactions (Monitor Closely): - CYP450 substrates: noscapine may alter metabolism of certain antibiotics. - Antacids: may affect oral absorption. - Alcohol: can potentiate sedative effects.

Frequently asked questions

What is Natterman Noscasan used for?+
Natterman Noscasan is used as a cough suppressant. It helps reduce the frequency and intensity of coughing associated with acute upper‑respiratory infections, chronic dry cough, and cough caused by bronchitis, providing symptomatic relief without opioid‑related effects.
How does noscapine work to suppress cough?+
Noscapine acts centrally by antagonizing sigma‑1 receptors in the brainstem’s cough centre. This modulation dampens the neuronal pathways that trigger the cough reflex, leading to a reduction in cough frequency and severity while sparing opioid‑type activity.
What is the usual dose of Natterman Noscasan?+
The appropriate dose of Natterman Noscasan is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Prescribers follow local guidelines and product labeling to set the regimen.
Is Natterman Noscasan safe during pregnancy or breastfeeding?+
Safety data for noscapine in pregnancy and lactation are limited. It is generally advised to avoid use during pregnancy unless the benefit outweighs the risk, and to exercise caution while breastfeeding, discussing potential exposure with a healthcare provider.
How do I order Natterman Noscasan from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Natterman Noscasan compare with other cough suppressants?+
Compared with opioid‑based suppressants such as codeine, noscapine offers cough relief without the risk of dependence or significant respiratory depression. Relative to dextromethorphan, it has a distinct sigma‑1 receptor mechanism and a favorable safety profile for patients where opioid avoidance is preferred.
What are the storage and handling requirements for Natterman Noscasan?+
Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.
How is Natterman Noscasan administered?+
Natterman Noscasan is taken orally. The tablet (or oral formulation) should be swallowed with water, following the dosing instructions provided by the prescriber. It is not intended for parenteral use.
What are the most serious risks associated with Natterman Noscasan?+
Serious adverse events, although rare, include allergic reactions such as rash, itching or swelling, hepatic dysfunction indicated by elevated liver enzymes, and neutropenia which can increase infection susceptibility. Patients should seek medical attention if any of these occur.
Who should not use Natterman Noscasan?+
Individuals with a known hypersensitivity to noscapine or any component of the formulation should avoid the product. Caution is also advised for patients with severe hepatic impairment, uncontrolled asthma, or those taking other central nervous system depressants without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Noscapine Hydrochloride Monohydrate
Route
Oral Use
Manufacturer
Vemedia Manufacturing B. V.
Origin
EU

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