GNH USA

Europe — EMA

Night Nurse Cold Remedy

GNH USA supplies Night Nurse Cold Remedy (Dextromethorphan), a combination cough suppressant, antihistamine and analgesic/antipyretic for relief of cough

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What is Dextromethorphan Hydrobromide, Promethazine Hydrochloride, Paracetamol?

Dextromethorphan Hydrobromide / Promethazine Hydrochloride / Paracetamol, the active ingredient in Night Nurse Cold Remedy, is a combination (cough suppressant, antihistamine, analgesic/antipyretic) presented as a combined oral formulation for oral use. It is intended to relieve common cold and flu symptoms such as cough, nasal congestion, headache, fever and sore throat in adults.

GNH USA supplies Night Nurse Cold Remedy as a licensed, GDP‑compliant international pharmaceutical supplier, which meets EU regulatory standards and serves pharmacies and clinics through its global worldwide network.

What is Dextromethorphan Hydrobromide, Promethazine Hydrochloride, Paracetamol used for?

Night Nurse Cold Remedy, a combination of dextromethorphan, promethazine and paracetamol, is used to manage symptoms of upper respiratory infections and influenza. - Cough: reduces the frequency and intensity of dry cough. - Nasal congestion: alleviates blocked nose and sinus pressure. - Headache/Fever: provides analgesic and antipyretic relief. - Sore throat: soothes throat discomfort associated with a cold. - General cold symptoms: improves overall comfort during viral upper respiratory illness.

What are the side effects of Dextromethorphan Hydrobromide, Promethazine Hydrochloride, Paracetamol?

Night Nurse Cold Remedy may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Drowsiness or sedation. - Dry mouth. - Dizziness or light‑headedness. - Nausea or mild gastrointestinal upset. - Blurred vision. - Constipation.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with rash, swelling or breathing difficulty. - Respiratory depression, especially when combined with other depressants. - Cardiac arrhythmias or palpitations. - Seizures. - Hepatic injury or elevated liver enzymes. - Blood dyscrasias such as neutropenia or thrombocytopenia.

What precautions apply to Dextromethorphan Hydrobromide, Promethazine Hydrochloride, Paracetamol?

Before using Night Nurse Cold Remedy, consider the following precautions. - Pregnancy: consult a healthcare professional before use. - Alcohol: avoid concurrent consumption as it may increase sedation. - Driving: do not operate machinery if drowsy or impaired. - Medical conditions: use with caution in patients with liver disease, glaucoma, asthma, or urinary retention. - Drug interactions: review all concomitant medications for potential interactions. - Store at ambient temperature: keep in the original pack, protect from moisture and heat.

What does Dextromethorphan Hydrobromide, Promethazine Hydrochloride, Paracetamol interact with?

Night Nurse Cold Remedy can interact with other medicines; review the following categories.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of serotonin syndrome with dextromethorphan. - Central nervous system depressants (e.g., benzodiazepines, opioids): additive sedation. - Alcohol: increased drowsiness and respiratory depression. - Other antihistamines: heightened anticholinergic effects.

Moderate Interactions (Monitor Closely): - Warfarin: paracetamol may enhance anticoagulant effect. - Anticholinergic drugs: cumulative dry mouth, urinary retention. - CYP2D6 inhibitors (e.g., fluoxetine): may increase dextromethorphan levels.

Frequently asked questions

What is Night Nurse Cold Remedy used for?+
Night Nurse Cold Remedy is an over‑the‑counter combination product that relieves common cold and flu symptoms such as cough, nasal congestion, headache, fever, and sore throat. It is intended for adult use to improve comfort during viral upper respiratory infections.
How does dextromethorphan work in this product?+
Dextromethorphan acts on the central nervous system as a sigma‑1 receptor agonist and an NMDA receptor antagonist. By modulating these pathways, it suppresses the cough reflex, reducing the frequency and intensity of dry, non‑productive coughs associated with colds.
What is the usual dose of Night Nurse Cold Remedy?+
The appropriate dose is determined by a qualified prescriber or pharmacist based on the patient’s age, weight, and clinical condition. Users should follow the specific instructions provided on the product label or by their healthcare professional and not exceed the recommended amount.
Is Night Nurse Cold Remedy safe during pregnancy or breastfeeding?+
Safety data for this combination in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using the product to weigh potential benefits against possible risks.
How do I order Night Nurse Cold Remedy from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Night Nurse Cold Remedy compare with other OTC cold medicines?+
Night Nurse combines a cough suppressant (dextromethorphan), an antihistamine (promethazine) and an analgesic/antipyretic (paracetamol) in one formulation. Compared with products that contain only one or two of these agents, it offers broader symptom coverage but may also carry a higher risk of sedation and drug‑drug interactions.
What are the storage and handling requirements for Night Nurse Cold Remedy?+
Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and excessive heat to maintain stability and potency throughout its shelf life.
How is Night Nurse Cold Remedy administered?+
The medication is taken orally, usually with a full glass of water. It should be swallowed whole and not chewed or crushed unless the label specifically permits an alternative method of administration.
What are the most serious risks to watch for while using Night Nurse Cold Remedy?+
Serious adverse reactions include severe allergic responses (anaphylaxis), respiratory depression, cardiac arrhythmias, seizures, significant liver injury, and blood disorders such as neutropenia. If any of these occur, seek immediate medical attention.
Who should not use Night Nurse Cold Remedy?+
Individuals with known hypersensitivity to any of the ingredients, those taking monoamine oxidase inhibitors, patients with severe liver impairment, uncontrolled glaucoma, or a history of severe asthma should avoid this product unless directed otherwise by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dextromethorphan Hydrobromide, Promethazine Hydrochloride, Paracetamol
Route
Oral Use
Manufacturer
Haleon Ireland Limited
Origin
EU

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