Night Nurse

Dextromethorphan Hydrobromide, the active ingredient in Night Nurse, is a combination antitussive, antihistamine and analgesic presented as an oral solution for oral use. It treats cough, nasal congestion, fever and related night‑time symptoms in adults and children.

GNH USA supplies Night Nurse as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Night Nurse, a combination antitussive, antihistamine and analgesic, provides symptomatic relief for common cold and flu presentations.

- Cough: suppresses the cough reflex to improve sleep and comfort. - Runny nose: reduces nasal discharge through antihistamine action. - Sore throat: eases throat irritation and pain. - Fever: lowers elevated body temperature. - Night‑time symptom relief: combines sedative and analgesic effects to help patients rest.

Night Nurse may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Drowsiness: increased sleepiness, especially at night. - Dry mouth: reduced salivation leading to throat discomfort. - Dizziness: light‑headed sensation after dosing. - Nausea: mild stomach upset.

Serious or Rare Side Effects: - Allergic reactions: rash, itching, swelling, or anaphylaxis. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Respiratory depression: slowed breathing, particularly when combined with other CNS depressants.

Before using Night Nurse, consider the following safety points.

- Follow label instructions: adhere to the recommended dose and interval. - Avoid alcohol: may intensify drowsiness and respiratory effects. - Do not operate machinery: sedation can impair alertness. - Use with caution in liver disease: paracetamol is metabolised hepatically. - Avoid in children under 6 years: safety not established for this age group. - Store at ambient temperature: keep in the original pack, protect from moisture.

Night Nurse can interact with other medicines; awareness of the level of interaction is important.

Major Interactions (Avoid): - Alcohol: enhances central nervous system depression. - MAO inhibitors: risk of serotonin syndrome with dextromethorphan. - Other CNS depressants (e.g., benzodiazepines, opioids): may cause excessive sedation. - Additional paracetamol‑containing products: increases risk of hepatotoxicity.

Moderate Interactions (Monitor Closely): - Antihistamines: additive sedative effect. - Anticholinergic drugs: may worsen dry mouth. - CYP2D6 inhibitors (e.g., fluoxetine, quinidine): raise dextromethorphan plasma levels.