Night Nurse

Dextromethorphan Hydrobromide, Promethazine Hydrochloride and Paracetamol, the active ingredients in Night Nurse, are a combination (cough suppressant, antihistamine, analgesic) presented as a syrup containing 10 mg dextromethorphan, 6.25 mg promethazine and 500 mg paracetamol per 5 mL for oral use. It relieves cough, nasal congestion, sore throat, headache, fever and helps with sleep in adults experiencing cold or flu symptoms.

GNH USA supplies Night Nurse as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Night Nurse is a combination oral liquid that addresses multiple symptoms of upper respiratory infections and flu.

- Cough: reduces cough frequency and intensity. - Nasal congestion: eases blocked nose and improves breathing. - Sore throat: soothes throat irritation and pain. - Headache: provides analgesic relief. - Fever: lowers elevated body temperature. - Sleep disturbance: promotes rest by alleviating discomfort and inducing mild sedation.

Night Nurse may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Drowsiness: feeling unusually sleepy. - Dry mouth: reduced salivation. - Dizziness: light‑headed sensation. - Blurred vision: temporary visual disturbance. - Nausea: mild stomach upset. - Constipation: reduced bowel movements.

Serious or Rare Side Effects: - Allergic reactions: rash, itching, swelling, or difficulty breathing. - Severe drowsiness: excessive sedation interfering with daily activities. - Respiratory depression: slowed breathing, especially when combined with other depressants. - Hallucinations or confusion: rare central nervous system effects. - Seizures: infrequent but serious neurological events.

Before using Night Nurse, consider the following safety measures.

- Do not exceed the recommended dose: follow prescriber or label instructions. - Avoid alcohol: may increase drowsiness and respiratory depression. - Use caution in liver disease: paracetamol is metabolised hepatically. - Avoid operating machinery if drowsy: sedation can impair alertness. - Consult a healthcare professional if pregnant or breastfeeding: safety data are limited. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Night Nurse can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of serotonin syndrome with dextromethorphan. - Central nervous system depressants (e.g., benzodiazepines, opioids): additive sedation and respiratory depression. - Alcohol: enhances drowsiness and depressant effects.

Moderate Interactions (Monitor Closely): - Anticholinergic drugs: may increase dry mouth and constipation. - Other antihistamines: can cause excessive sedation. - Warfarin: paracetamol may potentiate anticoagulant effect, requiring INR monitoring.