GNH USA

Europe — EMA

Nicorandil Viatris

GNH USA supplies Nicorandil Viatris (Nicorandil), a potassium channel opener/nitrate for stable angina pectoris. Request a quote for global supply today.

Nicorandil

Request sourcing

1
Pack/s

What is Nicorandil?

Nicorandil, the active ingredient in Nicorandil Viatris, is a potassium channel opener / nitrate presented as an oral tablet for oral use. It treats stable angina pectoris in adult patients by reducing chest pain episodes and improving exercise tolerance.

GNH USA supplies Nicorandil Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Nicorandil used for?

Nicorandil is used in the management of coronary artery disease and related angina syndromes.

- Stable angina pectoris: reduces the frequency of chest pain attacks and improves exercise capacity. - Chronic stable angina: decreases myocardial oxygen demand and alleviates ischemic symptoms. - Ischemic heart disease: helps relieve myocardial ischemia associated with angina.

What are the side effects of Nicorandil?

Nicorandil may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Headache: mild to moderate, often transient. - Flushing: warmth and redness of the skin. - Dizziness or light‑headedness, especially on standing. - Nausea or abdominal discomfort. - Palpitations or tachycardia. - Mild hypotension: reduced blood pressure without syncope.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure causing fainting. - Myocardial infarction: rare worsening of heart attack risk. - Stevens‑Johnson syndrome or severe skin reactions. - Angina exacerbation or new‑onset chest pain. - Anaphylactic or severe allergic reactions. - Hepatic dysfunction: abnormal liver enzymes.

What precautions apply to Nicorandil?

Before initiating Nicorandil therapy, consider the following safety measures.

- Contraindication: severe hypotension or cardiogenic shock. - Avoid use with other nitrates or potent vasodilators. - Caution in recent myocardial infarction: monitor cardiac status. - Monitor blood pressure regularly, especially after dose changes. - Pregnancy and lactation: safety not established; use only if benefit outweighs risk. - Discontinue gradually: abrupt cessation may precipitate rebound angina. - Store below 25°C: keep in the original pack, protect from moisture.

What does Nicorandil interact with?

Nicorandil can interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Phosphodiesterase‑5 inhibitors (e.g., sildenafil): risk of profound hypotension. - Other nitrates or nitrovasodilators: additive vasodilatory effect. - Potent vasodilators (e.g., hydralazine): may cause severe blood pressure drops.

Moderate Interactions (Monitor Closely): - Antihypertensives (ACE inhibitors, ARBs, beta‑blockers): monitor for additive blood pressure lowering. - Diuretics: may enhance hypotensive response. - Calcium channel blockers: observe for synergistic vasodilation. - Alcohol: can increase dizziness and hypotension. - Antiplatelet agents: watch for bleeding tendency.

Frequently asked questions

What is Nicorandil Viatris used for?+
Nicorandil Viatris is prescribed to manage stable angina pectoris, a condition characterized by chest pain due to reduced blood flow to the heart. It helps relieve symptoms, decrease the frequency of angina attacks, and improve exercise tolerance in adult patients with coronary artery disease.
How does Nicorandil work in the body?+
Nicorandil combines two mechanisms: it releases nitric oxide, which relaxes vascular smooth muscle, and it opens ATP‑sensitive potassium channels, causing arterial and venous dilation. This dual action reduces cardiac preload and afterload, lowering myocardial oxygen demand and alleviating angina.
What is the usual dose of Nicorandil Viatris?+
The specific dose of Nicorandil Viatris is determined by the prescribing healthcare professional based on the patient’s clinical condition, response, and tolerance. Dosage adjustments are made individually, and patients should follow the prescriber’s instructions without self‑adjusting the amount.
Is Nicorandil safe to use during pregnancy or breastfeeding?+
Safety data for Nicorandil in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.
How do I order Nicorandil Viatris from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Nicorandil compare with other anti‑anginal drugs?+
Nicorandil is unique because it combines nitrate‑like nitric‑oxide donation with potassium‑channel activation, offering both arterial and venous dilation. Compared with pure nitrates or beta‑blockers, it may provide additional symptom relief without the same degree of tolerance development, but individual response varies.
What are the storage and handling requirements for Nicorandil Viatris?+
Nicorandil Viatris should be stored below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments to maintain stability.
How is Nicorandil Viatris administered?+
Nicorandil Viatris is taken orally, usually as a tablet, with or without food as directed by the prescriber. The exact administration schedule, such as once or twice daily, is individualized based on the patient’s condition and therapeutic response.
What are the most serious risks associated with Nicorandil?+
Serious risks include severe hypotension, which can cause fainting, and rare but serious skin reactions such as Stevens‑Johnson syndrome. In rare cases, worsening angina or myocardial infarction may occur. Patients should seek immediate medical attention if they experience sudden severe chest pain, fainting, or extensive rash.
Who should not use Nicorandil Viatris?+
Nicorandil is contraindicated in patients with severe hypotension, cardiogenic shock, or recent myocardial infarction. Individuals taking other nitrates, PDE‑5 inhibitors, or potent vasodilators should avoid it unless closely supervised. Pregnant or breastfeeding women should only use it when clearly indicated by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Nicorandil
Route
Oral Use
Manufacturer
Viatris Sante
Origin
EU

Related products

Ikorel

Ikorel

Nicorandil

Sanofi Winthrop Industrie
EU
Nicolan

Nicolan

Nicorandil

G.L. Pharma Gmbh
EU
Nicorandil

Nicorandil

Nicorandil

Rivopharm Uk Ltd
EU
Nicorandil Almus

Nicorandil Almus

Nicorandil

Biogaran
EU