Mercilon 28

Desogestrel and Ethinylestradiol, the active ingredients in Mercilon 28, are a combined oral contraceptive presented as a 150 µg/30 µg tablet for oral use. It prevents pregnancy in women of reproductive age. GNH USA supplies Mercilon 28 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Mercilon 28 is a combined hormonal contraceptive used within the family planning and menstrual regulation pathway. - Contraception: prevents pregnancy in women of reproductive age by inhibiting ovulation. - Menstrual cycle regulation: helps achieve more predictable monthly periods. - Dysmenorrhea management: reduces menstrual pain associated with ovulatory cycles.

Common Side Effects: - Nausea: mild to moderate stomach upset, especially during the first cycles. - Breast tenderness: temporary swelling or discomfort of the breasts. - Headache: mild to moderate tension‑type headaches. - Spotting or breakthrough bleeding: irregular light bleeding between periods. - Mood changes: mild fluctuations in mood or irritability.

Serious or Rare Side Effects: - Venous thromboembolism: deep vein thrombosis or pulmonary embolism, requiring immediate medical attention. - Arterial thrombosis: stroke or myocardial infarction, especially in high‑risk individuals. - Severe hypertension: sudden increase in blood pressure that may lead to organ damage. - Hepatic adenoma: rare benign liver tumor. - Anaphylaxis: severe allergic reaction with rash, swelling, and breathing difficulty.

Before prescribing Mercilon 28, clinicians should evaluate individual risk factors and counsel patients on safe use. - Assess thrombotic risk: avoid in women with a history of clotting disorders or recent surgery. - Screen for hypertension: monitor blood pressure regularly during therapy. - Avoid smoking: especially in women over 35 years of age. - Evaluate liver function: contraindicated in severe hepatic impairment. - Pregnancy category X: do not use during pregnancy; advise effective contraception. - Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Mercilon 28 may interact with other medicines that affect hormone metabolism or clotting risk. Major Interactions (Avoid): - Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): markedly reduce contraceptive efficacy. - Rifampin: decreases plasma hormone levels, increasing risk of unintended pregnancy. - St. John's wort: may lower contraceptive effectiveness.

Moderate Interactions (Monitor Closely): - Antibiotics such as tetracycline: may slightly diminish hormonal protection. - Antifungals (e.g., fluconazole): can increase estrogen levels, raising side‑effect potential. - Selective serotonin reuptake inhibitors (SSRIs): may increase bleeding tendency when combined with hormonal therapy.