Marvelon 28

Desogestrel, the active ingredient in Marvelon 28, is a combined oral contraceptive presented as a 0.15 mg/0.02 mg tablet for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation and altering cervical mucus. Marvelon 28 also contains ethinylestradiol, which works synergistically to provide reliable contraceptive efficacy.

GNH USA supplies Marvelon 28 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Marvelon 28 is a combined oral contraceptive that acts on the hormonal regulation of the menstrual cycle to prevent pregnancy. - Contraception: Prevents unintended pregnancy in women of childbearing potential. - Menstrual cycle regulation: Provides more predictable monthly bleeding patterns. - Dysmenorrhea relief: Reduces painful menstrual cramps. - Acne management: Improves mild to moderate acne associated with hormonal fluctuations.

Common Side Effects: - Nausea: Mild to moderate stomach upset, especially during the first cycles. - Headache: Tension‑type or migraine‑like headaches may occur. - Breast tenderness: Transient swelling or discomfort of the breasts. - Spotting: Irregular breakthrough bleeding, particularly in early use.

Serious or Rare Side Effects: - Venous thromboembolism: Deep vein thrombosis or pulmonary embolism. - Hypertension: New‑onset or worsening high blood pressure. - Liver disorders: Jaundice or hepatic dysfunction. - Allergic reactions: Rash, itching, or swelling of the face and throat.

Before starting Marvelon 28, consider the following precautions: - Smoking: Women over 35 who smoke should avoid combined oral contraceptives. - Cardiovascular risk: Assess history of heart disease, stroke, or clotting disorders. - Liver disease: Use with caution in patients with active liver disease. - Pregnancy testing: Confirm non‑pregnant status before initiation. - Breastfeeding: Discuss alternatives with a healthcare provider if nursing. - Store at ambient temperature: Keep tablets below 25 °C in the original packaging, protected from moisture and light.

Marvelon 28 may interact with several medicines that affect hormone metabolism or clotting risk. Major Interactions (Avoid): - Antiepileptics (e.g., carbamazepine, phenytoin): Reduce contraceptive effectiveness. - Antiretrovirals (e.g., efavirenz): Decrease hormone levels, risking breakthrough bleeding. - Rifampicin: Increases hepatic metabolism, lowering efficacy. Moderate Interactions (Monitor Closely): - Antifungals (e.g., ketoconazole): May increase hormone concentrations. - St. John’s wort: Potentially lowers contraceptive efficacy. - Certain antibiotics (e.g., clarithromycin): May modestly affect hormone levels.