GNH USA

Europe — EMA

Maxitrol

GNH USA supplies Maxitrol (Neomycin/Polymyxin B/Dexamethasone), a antibiotic‑corticosteroid combination for bacterial conjunctivitis and ocular inflammation.

Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone

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What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone, the active ingredients in Maxitrol, are an antibiotic‑corticosteroid combination presented as an ophthalmic suspension for ocular use. The formulation treats bacterial eye infections and associated inflammation in patients requiring topical therapy.

GNH USA supplies Maxitrol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for global distribution, ensuring product integrity from manufacturing to the end‑user.

What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone used for?

Maxitrol is used in ophthalmology to treat bacterial infections and inflammatory conditions of the eye.

- Bacterial conjunctivitis: reduces bacterial load and associated inflammation in the conjunctiva. - Iritis and uveitis: diminishes intra‑ocular inflammation and pain. - Post‑operative eye inflammation: controls swelling and prevents infection after ocular surgery. - Keratitis: combats bacterial keratitis while alleviating corneal edema and discomfort.

What are the side effects of Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Adverse reactions may occur with topical use of Maxitrol. Patients should be monitored for any discomfort or unexpected changes in vision.

Common Side Effects: - Burning or stinging sensation upon instillation. - Transient blurred vision. - Mild ocular itching or redness. - Temporary foreign‑body feeling.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling or difficulty breathing. - Corneal ulceration or secondary ocular infection. - Increased intra‑ocular pressure leading to glaucoma. - Cataract formation with prolonged use.

What precautions apply to Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Use Maxitrol only under the direction of an eye‑care professional and observe the following precautions.

- Assess for viral or fungal eye infection: avoid use if non‑bacterial infection is suspected. - Monitor intra‑ocular pressure: regular checks are advised during extended therapy. - Limit duration of treatment: prolonged use may increase risk of cataract or glaucoma. - Avoid in patients with known hypersensitivity to any component. - Store at ambient temperature: keep in the original container, protect from moisture and light.

What does Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone interact with?

Topical Maxitrol may interact with other ophthalmic agents; consider the following interaction categories.

Major Interactions (Avoid): - Systemic aminoglycosides: may increase risk of nephrotoxicity when absorbed. - Systemic corticosteroids: can augment systemic glucocorticoid effects. - Antiviral eye drops (e.g., acyclovir): may reduce antiviral efficacy.

Moderate Interactions (Monitor Closely): - Other topical antibiotics: assess for additive antimicrobial effect and resistance. - Additional corticosteroid eye preparations: monitor for cumulative steroid exposure. - Ocular non‑steroidal anti‑inflammatory drugs: watch for corneal healing delays.

Frequently asked questions

What conditions is Maxitrol used to treat?+
Maxitrol is indicated for bacterial conjunctivitis, ocular inflammation such as iritis or uveitis, post‑operative eye inflammation, and bacterial keratitis. It combines an antibiotic and a corticosteroid to eliminate infection while reducing swelling and pain in the affected eye.
How does the combination of neomycin, polymyxin B, and dexamethasone work?+
Neomycin interferes with bacterial protein synthesis, and polymyxin B disrupts bacterial cell‑membrane integrity, providing broad‑spectrum antimicrobial action. Dexamethasone binds to glucocorticoid receptors, altering gene expression to suppress inflammatory mediators, thereby decreasing edema, leukocyte infiltration, and pain.
What is the usual dose of Maxitrol?+
The dosing regimen for Maxitrol is determined by the prescribing eye‑care professional based on the specific condition, severity, and patient response. The prescriber will provide instructions on the number of drops, frequency, and duration of therapy.
Is Maxitrol safe to use during pregnancy or breastfeeding?+
Safety data for Maxitrol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.
How do I order Maxitrol from GNH USA?+
To request Maxitrol, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Maxitrol compare with other ophthalmic antibiotics?+
Compared with single‑agent antibiotic eye drops, Maxitrol offers the added benefit of a corticosteroid, which can more rapidly reduce inflammation. However, the steroid component requires careful monitoring for intra‑ocular pressure and cataract risk, whereas pure antibiotics lack these steroid‑related concerns.
What are the recommended storage conditions for Maxitrol?+
Store Maxitrol at ambient temperature, below 25 °C. Keep the bottle in its original packaging, protect it from moisture and direct sunlight, and ensure the cap is tightly closed to maintain sterility.
How is Maxitrol administered?+
Maxitrol is applied as eye drops. The prescribed number of drops is placed into the lower conjunctival sac of the affected eye(s) using the provided dropper, typically avoiding contact between the tip and the eye or surrounding tissues.
What are the most serious risks associated with Maxitrol?+
Serious risks include severe allergic reactions (anaphylaxis), corneal ulceration or secondary infection, and steroid‑related complications such as increased intra‑ocular pressure, glaucoma, or cataract formation, especially with prolonged use.
Who should not use Maxitrol?+
Maxitrol should not be used by individuals with known hypersensitivity to neomycin, polymyxin B, dexamethasone, or any excipients in the formulation. It is also contraindicated in viral, fungal, or protozoal eye infections where a steroid could worsen the condition.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone
Route
Ocular Use
Manufacturer
Novartis Pharmaceuticals Uk Limited
Origin
EU

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