GNH USA

Europe — EMA

Isopto Maxitrol

GNH USA supplies Isopto Maxitrol (Neomycin, Polymyxin B, Dexamethasone) for conjunctivitis, keratitis and eye inflammation. Request a quote for supply.

Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone

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What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Neomycin sulfate, Polymyxin B sulfate and Dexamethasone, the active ingredients in Isopto Maxitrol, are a combination antibiotic corticosteroid presented as an ophthalmic suspension for ocular use. It treats bacterial eye infections and associated inflammation in both adults and children as directed by a healthcare professional.

GNH USA supplies Isopto Maxitrol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution and reliable service.

What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone used for?

Isopto Maxitrol, a combination antibiotic corticosteroid, acts on bacterial ocular infections and inflammatory processes.

- Bacterial conjunctivitis: reduces bacterial load and alleviates associated redness and discharge. - Keratitis: treats corneal infection and helps control inflammation to preserve vision. - Ocular inflammation: diminishes swelling, pain and photophobia caused by inflammatory eye conditions.

What are the side effects of Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Adverse ocular reactions may occur with Isopto Maxitrol use.

Common Side Effects: - Burning or stinging sensation upon instillation. - Temporary blurred vision. - Mild eye irritation or itching. - Redness of the conjunctiva. - Tearing or watery discharge.

Serious or Rare Side Effects: - Increased intra‑ocular pressure leading to glaucoma. - Secondary ocular infection or fungal overgrowth. - Corneal ulceration or epithelial defect. - Allergic hypersensitivity reaction (e.g., rash, swelling). - Vision loss.

What precautions apply to Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Before prescribing Isopto Maxitrol, consider the following precautions. - Pregnancy: safety not established; use only if potential benefit justifies risk. - Breastfeeding: unknown excretion; evaluate risk versus benefit. - Pre‑existing glaucoma or ocular hypertension: monitor intra‑ocular pressure closely. - Viral eye infections (e.g., herpes simplex): avoid as steroids may exacerbate infection. - Contact lens wearers: remove lenses before instillation and wait before reinserting. - Store at ambient temperature: keep in original container, protect from light and moisture.

What does Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone interact with?

Isopto Maxitrol may interact with other ophthalmic or systemic agents.

Major Interactions (Avoid): - Systemic corticosteroids: additive immunosuppression may increase infection risk. - Other topical antibiotics: potential for antagonistic bacterial resistance.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: may reduce steroid efficacy. - Anticholinergic eye medications: possible delayed wound healing. - Systemic aminoglycoside antibiotics: monitor for additive nephrotoxicity (though minimal ocular absorption).

Frequently asked questions

What is Isopto Maxitrol used for?+
Isopto Maxitrol is a prescription ophthalmic suspension that combines the antibiotics neomycin sulfate and polymyxin B sulfate with the corticosteroid dexamethasone. It is indicated for the treatment of bacterial eye infections such as conjunctivitis and keratitis, and for reducing inflammation associated with these conditions.
How does neomycin, polymyxin B and dexamethasone work?+
Neomycin interferes with bacterial protein synthesis by binding the 30 S ribosomal subunit, while polymyxin B disrupts the bacterial cell‑membrane, causing rapid cell death. Dexamethasone activates glucocorticoid receptors, altering gene transcription to suppress inflammatory cytokines, reduce vascular leakage and limit leukocyte migration, thereby controlling ocular inflammation.
What is the usual dose of Isopto Maxitrol?+
The dosing regimen for Isopto Maxitrol is determined by the prescribing clinician based on the severity of the infection, patient age and response to therapy. Typical instructions involve instilling one to two drops into the affected eye(s) at intervals specified by the healthcare professional.
Is Isopto Maxitrol safe in pregnancy or breastfeeding?+
Safety data for neomycin, polymyxin B and dexamethasone in pregnancy or lactation are limited. The product should be used only if the potential benefit outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.
How do I order Isopto Maxitrol from GNH USA?+
To request Isopto Maxitrol, submit an enquiry on the product page at gnh-usa.com, indicating the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Isopto Maxitrol compare with other eye antibiotics?+
Compared with single‑agent antibiotic drops, Isopto Maxitrol offers both antibacterial activity (neomycin and polymyxin B) and anti‑inflammatory action (dexamethasone) in one formulation, which can simplify treatment regimens. However, clinicians may prefer separate agents when a steroid is contraindicated or when targeting specific bacterial spectra.
How should Isopto Maxitrol be stored and handled?+
The suspension should be stored at room temperature, away from direct sunlight and moisture. Keep the vial tightly closed when not in use, and discard any remaining product after the labeled period after opening, as recommended by the manufacturer.
How is Isopto Maxitrol administered?+
Isopto Maxitrol is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and place the prescribed number of drops into the conjunctival sac. Contact lenses should be removed before instillation and re‑inserted after a suitable interval.
What are the most serious risks associated with Isopto Maxitrol?+
Serious adverse events can include a rise in intra‑ocular pressure leading to glaucoma, secondary ocular infections such as fungal overgrowth, corneal ulceration, and severe allergic reactions that may threaten vision. Any sudden vision changes or intense eye pain should prompt immediate medical evaluation.
Who should not use Isopto Maxitrol?+
Patients with known hypersensitivity to neomycin, polymyxin B, dexamethasone or any component of the formulation should avoid the product. It is also contraindicated in viral eye infections like herpes simplex keratitis, and should be used with caution in individuals with uncontrolled glaucoma or ocular hypertension.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone
Route
Ocular Use
Manufacturer
Novartis Ireland Limited
Origin
EU

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