Isopto-Max

Neomycin sulfate, Polymyxin B sulfate, and Dexamethasone, the active ingredients in Isopto-Max, are a corticosteroid/antibiotic combination presented as a 3%/0.1%/0.1% ophthalmic suspension for ocular use. It treats bacterial and inflammatory eye conditions such as conjunctivitis and postoperative inflammation in both adults and children.

GNH USA supplies Isopto-Max as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand through reliable logistics and dedicated customer support.

Isopto-Max is indicated for ocular conditions involving bacterial infection or inflammation. - Bacterial conjunctivitis: reduces bacterial load and alleviates associated redness and discharge. - Allergic conjunctivitis: diminishes inflammatory response and relieves itching and swelling. - Post‑operative ocular inflammation: controls inflammation and prevents infection after eye surgery. - General ocular inflammation: provides anti‑inflammatory effect and protects against secondary bacterial infection.

Ophthalmic use of Isopto-Max may be associated with local and systemic adverse reactions.

Common Side Effects: - Burning or stinging sensation upon instillation, usually lasting a few minutes. - Transient blurred vision that resolves shortly after dosing. - Mild itching or foreign‑body feeling in the treated eye. - Increased tear production or watery discharge.

Serious or Rare Side Effects: - Elevated intra‑ocular pressure that may progress to glaucoma if untreated. - Development of cataract with prolonged corticosteroid exposure. - Corneal ulceration or secondary ocular infection requiring medical attention. - Severe allergic reaction such as angio‑edema, urticaria, or anaphylaxis.

Before using Isopto-Max, consider the following precautions to minimize risks. - Avoid use in viral eye infections: risk of worsening infection. - Do not use in patients with known hypersensitivity to neomycin, polymyxin B, dexamethasone or any excipients. - Monitor intra‑ocular pressure: corticosteroid component may raise pressure. - Limit duration of therapy: prolonged use increases risk of cataract or glaucoma. - Use with caution in pregnancy: safety not established; weigh benefits against potential risks. - Store at room temperature: keep in original container, protect from light and moisture.

Isopto-Max can interact with other ophthalmic or systemic agents; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid): - Concurrent use of other ocular corticosteroids: additive risk of increased intra‑ocular pressure. - Systemic aminoglycosides (e.g., gentamicin): potential nephrotoxicity potentiation with neomycin. - Contact lens wear during treatment: may trap suspension and increase irritation.

Moderate Interactions (Monitor Closely): - Co‑administration with other topical antibiotics: possible additive bacterial resistance. - Use with nonsteroidal anti‑inflammatory eye drops: may affect healing dynamics. - Systemic corticosteroids: increased overall steroid exposure may enhance systemic effects.