GNH USA

Europe — EMA

Maxitrol

GNH USA supplies Maxitrol (Neomycin, Polymyxin B, Dexamethasone), a combination antibiotic and corticosteroid for bacterial conjunctivitis and postoperative

Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone

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What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Neomycin Sulfate, Polymyxin B Sulfate and Dexamethasone, the active ingredients in Maxitrol, are a combination antibiotic and corticosteroid presented as a 0.1% dexamethasone/Neomycin 3.5 mg/mL/Polymyxin B 10,000 IU/mL ophthalmic suspension for ocular use. It treats bacterial conjunctivitis and other ocular inflammatory conditions with bacterial involvement in adults and children as prescribed. It is indicated for use in patients requiring topical treatment of bacterial eye infections and associated inflammation.

GNH USA supplies Maxitrol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing and regulatory support for ophthalmic therapies.

What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone used for?

Maxitrol is used to manage bacterial eye infections and associated inflammatory responses. - Bacterial conjunctivitis: reduces bacterial load and inflammation, promoting faster resolution of redness and discharge. - Keratitis: controls infection and swelling of the cornea, aiding visual recovery. - Post‑operative ocular inflammation: limits postoperative swelling and prevents secondary bacterial contamination. - Other ocular inflammatory conditions with bacterial involvement: alleviates pain, redness, and purulent discharge while treating the underlying infection.

What are the side effects of Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Common Side Effects: - Stinging or burning sensation upon instillation. - Transient blurred vision. - Mild ocular itching or irritation. - Redness of the conjunctiva. - Foreign‑body feeling in the eye. - Temporary tearing.

Serious or Rare Side Effects: - Allergic reaction with swelling, rash, or hives. - Severe eye pain or worsening redness. - Rapid vision loss or sudden visual disturbance. - Corneal ulceration or perforation. - Increased intra‑ocular pressure leading to glaucoma. - Secondary ocular infection due to altered flora.

What precautions apply to Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Before using Maxitrol, consider the following precautions: - Hypersensitivity: discontinue if any signs of allergic reaction occur. - Contact lens wear: remove lenses before instillation and wait at least 15 minutes before reinserting. - Pre‑existing glaucoma or ocular hypertension: monitor intra‑ocular pressure regularly. - Viral or fungal eye infections: avoid use as it may exacerbate non‑bacterial infections. - Systemic aminoglycoside therapy: use with caution due to potential additive toxicity. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone interact with?

Maxitrol may interact with other ophthalmic agents and systemic drugs. Major Interactions (Avoid): - Concurrent use of other topical corticosteroids: may increase risk of elevated intra‑ocular pressure. - Systemic immunosuppressants: could reduce local anti‑infective efficacy. Moderate Interactions (Monitor Closely): - Other ophthalmic antibiotics: assess for additive toxicity or reduced effectiveness. - Contact lens solutions containing preservatives: may cause increased ocular irritation. - Systemic nephrotoxic drugs: monitor renal function if prolonged ocular absorption is suspected.

Frequently asked questions

What conditions is Maxitrol used to treat?+
Maxitrol is prescribed for bacterial eye infections such as conjunctivitis and keratitis, as well as for postoperative ocular inflammation and other inflammatory eye conditions where bacterial involvement is present. It combines an antibiotic and a corticosteroid to both eliminate pathogens and reduce swelling, redness, and pain.
How does the combination of neomycin, polymyxin B, and dexamethasone work?+
Neomycin and polymyxin B act on bacterial cell membranes, causing rapid cell death and reducing infection. Dexamethasone binds to glucocorticoid receptors in ocular tissues, suppressing inflammatory mediators like prostaglandins and cytokines, which decreases swelling, redness, and discomfort.
What is the usual dose of Maxitrol?+
The dosing regimen for Maxitrol is determined by the prescribing clinician based on the specific eye condition, severity, and patient factors. The prescriber will provide instructions on the number of drops, frequency, and duration of therapy.
Is Maxitrol safe to use during pregnancy or breastfeeding?+
Safety data for Maxitrol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.
How do I order Maxitrol from GNH USA?+
To order Maxitrol, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details, and any required import documentation.
How does Maxitrol compare with other ophthalmic antibiotics?+
Compared with single‑agent ophthalmic antibiotics, Maxitrol offers the added benefit of a corticosteroid, providing both antimicrobial activity and anti‑inflammatory effect. This can reduce treatment time for infections accompanied by significant inflammation, but it also requires careful monitoring for steroid‑related side effects.
What are the storage requirements for Maxitrol?+
Store Maxitrol at room temperature, ideally below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from direct light and moisture, and discard any product that appears discolored or contains particles.
How is Maxitrol administered?+
Maxitrol is applied as an ophthalmic suspension. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. Close the eye gently for a few seconds and avoid blinking excessively.
What are the most serious risks associated with Maxitrol?+
Serious risks include allergic reactions such as swelling, rash, or hives; severe eye pain, rapid vision loss, or corneal ulceration; and increased intra‑ocular pressure that can lead to glaucoma. Any of these symptoms require immediate medical attention.
Who should not use Maxitrol?+
Maxitrol should not be used by individuals with known hypersensitivity to neomycin, polymyxin B, dexamethasone, or any component of the formulation. It is also contraindicated in viral or fungal eye infections and should be used with caution in patients with uncontrolled glaucoma or ocular hypertension.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone
Route
Ocular Use
Manufacturer
Novartis Farmacéutica S.A.
Origin
EU

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