GNH USA

Europe — EMA

Maxitrol

GNH USA supplies Maxitrol (Neomycin/Polymyxin B/Dexamethasone), a antibiotic corticosteroid combination for bacterial conjunctivitis, keratitis

Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone

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What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Neomycin sulfate / Polymyxin B sulfate / Dexamethasone, the active ingredient in Maxitrol, is an antibiotic corticosteroid combination presented as a 0.5% w/v neomycin, 0.5% w/v polymyxin B and 0.1% w/v dexamethasone ophthalmic suspension for ocular use. It is indicated for the treatment of bacterial conjunctivitis, keratitis and postoperative ocular inflammation in adult and pediatric patients.

GNH USA supplies Maxitrol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone used for?

Maxitrol acts on bacterial ocular infections and associated inflammatory processes. - Bacterial conjunctivitis: reduces bacterial load and inflammation, accelerating symptom relief. - Keratitis: eradicates pathogenic organisms and diminishes corneal inflammation to preserve visual acuity. - Post‑operative ocular inflammation: controls postoperative swelling and pain while preventing secondary infection. - General ocular inflammation: provides anti‑inflammatory effect in mixed infectious‑inflammatory eye conditions.

What are the side effects of Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Adverse reactions may occur with ocular administration of Maxitrol.

Common Side Effects: - Burning or stinging sensation upon instillation. - Temporary blurred vision. - Mild conjunctival hyperemia. - Foreign‑body sensation. - Increased tear production. - Mild itching or irritation.

Serious or Rare Side Effects: - Allergic contact dermatitis or severe hypersensitivity reaction. - Elevated intra‑ocular pressure leading to glaucoma. - Secondary fungal or viral eye infection. - Cataract formation with prolonged use. - Corneal ulceration or perforation. - Systemic absorption causing adrenal suppression (very rare).

What precautions apply to Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Use of Maxitrol requires careful consideration of patient‑specific factors. - Pregnancy: safety not established; avoid unless benefit outweighs risk. - Breastfeeding: unknown excretion; use with caution. - Contact lens wearers: discontinue lenses during therapy and resume after treatment completion. - Duration: limit use to the prescribed period to reduce risk of steroid‑related complications. - Monitor: watch for signs of secondary infection or rising intra‑ocular pressure. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone interact with?

Maxitrol may interact with other ocular or systemic agents.

Major Interactions (Avoid): - Systemic corticosteroids: additive immunosuppression may increase infection risk. - Topical antifungal eye drops: may reduce efficacy of the antibacterial components.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: increased ocular irritation. - Topical ocular anesthetics: heightened corneal toxicity potential. - Systemic immunosuppressants: monitor for opportunistic ocular infections.

Frequently asked questions

What conditions is Maxitrol used to treat?+
Maxitrol is prescribed for bacterial eye infections such as conjunctivitis and keratitis, as well as for postoperative ocular inflammation and other inflammatory eye conditions where both antimicrobial and anti‑inflammatory actions are needed.
How does the combination of Neomycin, Polymyxin B and Dexamethasone work?+
Neomycin interferes with bacterial protein synthesis, Polymyxin B disrupts bacterial cell membranes, and Dexamethasone binds glucocorticoid receptors to suppress inflammatory gene expression. Together they eliminate pathogens and reduce ocular inflammation.
What is the usual dosing regimen for Maxitrol?+
The dosing schedule for Maxitrol is determined by the prescribing clinician based on the severity of the infection, patient age, and response to therapy. Patients should follow the exact instructions provided on the prescription label.
Is Maxitrol safe to use during pregnancy or breastfeeding?+
Safety data for Maxitrol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by a qualified health professional.
How do I order Maxitrol from GNH USA?+
To request Maxitrol, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Maxitrol compare with other ophthalmic antibiotics?+
Unlike single‑agent eye drops, Maxitrol combines two broad‑spectrum antibiotics with a corticosteroid, offering simultaneous antimicrobial and anti‑inflammatory effects. This can simplify therapy for mixed infections but requires careful monitoring for steroid‑related side effects.
What are the recommended storage conditions for Maxitrol?+
Store Maxitrol at room temperature, below 25 °C, in the original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any product that appears discolored or contains particles.
How is Maxitrol administered?+
Maxitrol is applied topically to the eye as an ophthalmic suspension. The prescribed number of drops is placed into the conjunctival sac of the affected eye(s) according to the clinician’s directions, typically using a clean fingertip to avoid contamination.
What are the most serious risks associated with Maxitrol?+
Serious risks include allergic reactions, increased intra‑ocular pressure that may lead to glaucoma, secondary fungal or viral infections, and, with prolonged use, cataract formation. Patients should report any worsening vision, pain, or redness promptly.
Who should not use Maxitrol?+
Maxitrol is contraindicated in patients with known hypersensitivity to any of its components, in those with viral eye infections such as herpes simplex, and in individuals with uncontrolled glaucoma or active ocular tuberculosis.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone
Route
Ocular Use
Manufacturer
Novartis Europharm Limited
Origin
EU

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