GNH USA

Europe — EMA

Maxitrol

GNH USA supplies Maxitrol (Neomycin, Polymyxin B, Dexamethasone), a corticosteroid/antibiotic combination for bacterial and inflammatory eye conditions.

Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone

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What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Neomycin Sulfate, Polymyxin B Sulfate and Dexamethasone, the active ingredients in Maxitrol, are a corticosteroid/antibiotic combination presented as an ophthalmic suspension for ocular use. It treats bacterial and inflammatory eye conditions such as conjunctivitis, allergic reactions and post‑operative inflammation in both adults and children.

GNH USA supplies Maxitrol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone used for?

Maxitrol is used to manage ocular infections and inflammation across several common eye conditions.

- Bacterial conjunctivitis: reduces bacterial load and associated inflammation in infected eyes. - Allergic conjunctivitis: alleviates allergic swelling, redness and itching. - Post‑operative eye inflammation: controls inflammation and prevents infection after eye surgery. - Ocular inflammation (non‑infectious): diminishes swelling, pain and redness in various inflammatory eye disorders.

What are the side effects of Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Common Side Effects: - Burning or stinging sensation upon instillation. - Transient blurred vision. - Mild eye irritation or itching. - Temporary foreign‑body feeling. - Slight eyelid edema. - Mild conjunctival redness.

Serious or Rare Side Effects: - Allergic reaction with swelling, rash or hives. - Severe eye pain or worsening redness. - Vision loss or sudden decrease in visual acuity. - Secondary ocular infection or corneal ulceration. - Elevated intra‑ocular pressure leading to glaucoma. - Persistent or worsening inflammation despite therapy.

What precautions apply to Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Before using Maxitrol, consider the following precautions. - Confirm bacterial infection: ensure the condition is bacterial before initiating therapy. - Avoid viral or fungal eye infections: corticosteroids may exacerbate non‑bacterial pathogens. - Monitor intra‑ocular pressure: patients with steroid‑responsive glaucoma need regular pressure checks. - Limit duration: do not exceed the prescribed treatment period without medical review. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone interact with?

Maxitrol may interact with other ophthalmic agents.

Major Interactions (Avoid): - Systemic corticosteroids: may increase systemic steroid exposure. - Contact lens wear: can enhance drug absorption and cause irritation. - Concurrent ophthalmic antibiotics: may lead to additive toxicity.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: may affect healing response. - Anticholinergic eye drops: could reduce tear production and exacerbate dryness. - Topical ocular anesthetics: may mask early signs of irritation or infection.

Frequently asked questions

What is Maxitrol used for?+
Maxitrol is an ophthalmic suspension indicated for the treatment of bacterial conjunctivitis, allergic conjunctivitis, ocular inflammation and post‑operative eye inflammation. It combines an antibiotic and a corticosteroid to address both infection and inflammation in the eye.
How does the combination of neomycin, polymyxin B and dexamethasone work?+
Neomycin and polymyxin B act as antibiotics: neomycin inhibits bacterial protein synthesis, while polymyxin B disrupts the cell membrane of gram‑negative bacteria. Dexamethasone is a glucocorticoid that binds intracellular receptors to suppress inflammatory pathways, reducing swelling, redness and pain.
What is the usual dose of Maxitrol?+
The dosing regimen for Maxitrol is determined by the prescribing clinician based on the specific condition, severity and patient factors. The prescriber will provide instructions on the number of drops, frequency and duration of therapy.
Is Maxitrol safe to use during pregnancy or breastfeeding?+
Safety data for Maxitrol in pregnancy and lactation are limited. The decision to use it should be made by a healthcare professional after weighing potential benefits against possible risks to the mother and fetus or infant.
How do I order Maxitrol from GNH USA?+
To order Maxitrol, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Maxitrol compare with other eye‑drop treatments?+
Compared with single‑agent antibiotic drops, Maxitrol offers both antibacterial and anti‑inflammatory activity, which can simplify therapy for mixed infections and inflammation. Compared with steroid‑only drops, it adds protection against bacterial contamination, but it also carries the combined safety profile of both drug classes.
What are the storage and handling requirements for Maxitrol?+
Store Maxitrol at room temperature, preferably below 25 °C. Keep the bottle tightly closed, protect it from direct sunlight and moisture, and do not freeze. If the suspension appears discolored or contains particles, discard it and obtain a new supply.
How is Maxitrol administered?+
Maxitrol is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds to allow absorption.
What are the most serious risks associated with Maxitrol?+
Serious risks include allergic reactions such as severe eye swelling or rash, secondary ocular infections, corneal ulceration, and a rise in intra‑ocular pressure that can lead to glaucoma. Any sudden worsening of vision or pain should prompt immediate medical evaluation.
Who should not use Maxitrol?+
Maxitrol should be avoided in patients with known hypersensitivity to any of its components, in viral or fungal eye infections, and in individuals with uncontrolled glaucoma or steroid‑responsive intra‑ocular pressure elevations unless closely monitored by an eye specialist.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone
Route
Ocular Use
Manufacturer
Novartis Ireland Limited
Origin
EU

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