GNH USA

Europe — EMA

Maxitrol

GNH USA supplies Maxitrol (Neomycin, Polymyxin B, Dexamethasone), an antibiotic and corticosteroid for bacterial conjunctivitis, ocular inflammation

Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone

Request sourcing

1
Pack/s

What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Neomycin sulfate, Polymyxin B sulfate, Dexamethasone, the active ingredients in Maxitrol, are an antibiotic and corticosteroid presented as a 3%/0.1%/0.5% ophthalmic suspension for ocular (topical) use. It treats bacterial eye infections and reduces inflammation in patients of all ages, helping to clear infection, alleviate pain and prevent scarring.

GNH USA supplies Maxitrol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing, regulatory support and consistent quality for ophthalmic treatments. The company adheres to stringent Good Distribution Practice standards and offers flexible shipping options to meet global demand.

What is Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone used for?

Maxitrol combines antibiotic and anti‑inflammatory actions to manage ocular bacterial infections and related inflammation.

- Bacterial conjunctivitis: reduces bacterial load and resolves infection. - Ocular inflammation: decreases swelling, redness and discomfort. - Post‑operative inflammation: controls inflammation after eye surgery and promotes healing. - Keratitis: treats bacterial keratitis and limits corneal damage.

What are the side effects of Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Topical administration of Maxitrol may be associated with ocular and systemic adverse reactions.

Common Side Effects: - Burning or stinging sensation: transient discomfort upon instillation. - Blurred vision: temporary visual disturbance that resolves after blinking. - Itching or redness: mild irritation of the conjunctiva. - Increased intra‑ocular pressure: mild rise detectable on routine check.

Serious or Rare Side Effects: - Allergic reaction: swelling, rash or hives requiring discontinuation. - Corneal ulceration: worsening of corneal integrity necessitating urgent care. - Secondary ocular infection: overgrowth of non‑susceptible organisms. - Glaucoma or cataract formation: prolonged steroid exposure may accelerate these conditions.

What precautions apply to Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone?

Before prescribing Maxitrol, clinicians should consider several safety measures.

- Hypersensitivity: avoid use in patients with known allergy to neomycin, polymyxin B, dexamethasone or any excipients. - Viral infections: do not use for viral conjunctivitis such as adenovirus, as steroids may worsen infection. - Intra‑ocular pressure: monitor pressure during prolonged therapy, especially in glaucoma patients. - Contact lens wear: discontinue lenses before and after instillation to prevent irritation. - Pregnancy and lactation: safety not established; use only if benefit outweighs risk. - Store at room temperature: keep in original container, protect from light and moisture.

What does Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone interact with?

Maxitrol may interact with other ophthalmic or systemic agents.

Major Interactions (Avoid): - Concurrent ophthalmic corticosteroids: additive risk of elevated intra‑ocular pressure and cataract. - Use with contact lenses: may cause lens contamination and irritation. - Systemic aminoglycosides: potential additive nephrotoxicity if systemic absorption occurs (rare).

Moderate Interactions (Monitor Closely): - Topical non‑steroidal anti‑inflammatory drugs (NSAIDs): increased risk of corneal melting. - Other topical antibiotics: possible antagonistic effect reducing efficacy. - Systemic immunosuppressants: may diminish infection control, requiring closer observation.

Frequently asked questions

What is Maxitrol used for?+
Maxitrol is an ophthalmic suspension that combines two antibiotics with a corticosteroid. It is prescribed to treat bacterial eye infections such as conjunctivitis and keratitis, and to reduce inflammation after eye surgery or in other inflammatory ocular conditions.
How does neomycin, polymyxin B and dexamethasone work together?+
Neomycin blocks bacterial protein synthesis, while polymyxin B disrupts the bacterial cell membrane, both killing susceptible microbes. Dexamethasone activates glucocorticoid receptors, suppressing inflammatory cytokines and reducing swelling, redness and pain in the eye.
What is the usual dose of Maxitrol?+
The dosing regimen for Maxitrol is determined by the prescribing clinician based on the specific infection or inflammation being treated. Typical regimens involve one to two drops per eye several times daily, but the exact schedule must follow the prescriber’s instructions.
Is Maxitrol safe during pregnancy or breastfeeding?+
Safety data for Maxitrol in pregnancy and lactation are limited. It is classified as a category where the benefit‑risk balance must be evaluated by the healthcare provider. Use is generally reserved for situations where the potential benefit justifies any possible risk to the fetus or infant.
How do I order Maxitrol from GNH USA?+
To request Maxitrol, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Maxitrol compare with other ophthalmic antibiotics?+
Compared with single‑agent eye drops, Maxitrol offers a broad‑spectrum antibacterial effect from neomycin and polymyxin B plus anti‑inflammatory action from dexamethasone. This dual approach can simplify therapy for mixed infections with inflammation, but clinicians must weigh the added steroid‑related risks against alternatives that contain only antibiotics.
How should Maxitrol be stored and handled?+
Maxitrol should be stored at room temperature, below 25 °C, in its original container. Protect the suspension from direct light and moisture. Keep the bottle tightly closed when not in use and discard any remaining product after the labeled period once opened.
How is Maxitrol administered?+
Maxitrol is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow the medication to spread, and contact lenses should be removed before use.
What are the most serious risks to watch for with Maxitrol?+
Serious risks include allergic reactions such as swelling or rash, development of corneal ulcers, secondary infections from resistant organisms, and steroid‑related complications like increased intra‑ocular pressure, glaucoma or cataract formation, especially with prolonged use.
Who should not use Maxitrol?+
Maxitrol should be avoided in individuals with known hypersensitivity to neomycin, polymyxin B, dexamethasone or any formulation excipients. It is also contraindicated for viral eye infections, such as adenoviral conjunctivitis, and in patients where steroid use is prohibited, such as those with uncontrolled glaucoma.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Neomycin Sulfate, Polymyxin B Sulfate, Dexamethasone
Route
Ocular Use
Manufacturer
Novartis Healthcare A/S
Origin
EU

Related products