Lactulosum Aflofarm

Lactulose, the active ingredient in Lactulosum Aflofarm, is an osmotic laxative presented as a liquid solution for oral use. It treats constipation and hepatic encephalopathy in patients who require gentle bowel cleansing and ammonia reduction. GNH USA supplies Lactulosum Aflofarm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lactulose is used as an osmotic laxative and ammonia‑lowering agent in the following conditions: - Constipation: softens stool and promotes regular bowel movements. - Hepatic encephalopathy: lowers intestinal ammonia absorption, helping improve mental status. - Prevention of hepatic encephalopathy recurrence: maintains low ammonia levels to reduce the risk of episodic neurocognitive decline.

Lactulose may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Abdominal bloating: sensation of fullness or swelling in the abdomen. - Flatulence: increased intestinal gas production. - Diarrhoea: loose, watery stools, especially at higher doses. - Nausea: feeling of sickness or urge to vomit. - Abdominal cramping: painful muscle contractions in the gut. - Thirst: increased desire for fluids.

Serious or Rare Side Effects: - Severe electrolyte imbalance: notably low potassium or sodium levels. - Dehydration: excessive fluid loss leading to dizziness or low blood pressure. - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Severe abdominal pain: persistent, intense pain requiring medical evaluation.

Before initiating Lactulosum Aflofarm, consider the following safety measures: - Renal function assessment: evaluate kidney status to avoid accumulation. - Electrolyte monitoring: check serum potassium and sodium periodically. - Diabetes caution: monitor blood glucose as lactulose can affect carbohydrate metabolism. - Intestinal obstruction avoidance: do not use in patients with known blockage. - Hepatic impairment dose adjustment: consider lower doses in severe liver disease. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Lactulose can interact with other medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid): - Antidiarrhoeal agents (e.g., loperamide): may counteract lactulose’s laxative effect. - Concurrent strong laxatives: increase risk of severe electrolyte disturbances.

Moderate Interactions (Monitor Closely): - Diabetes medications: lactulose may alter glucose control; monitor blood sugar. - Mineral supplements (e.g., magnesium): additive osmotic effect may enhance diarrhoea. - Oral antibiotics: may modify gut flora, potentially affecting lactulose metabolism.