Lactulose Fresenius

Lactulose, the active ingredient in Lactulose Fresenius, is an osmotic laxative presented as a liquid for oral use. It is indicated for the treatment of constipation and hepatic encephalopathy in adult patients, helping to soften stools and lower intestinal ammonia levels.

GNH USA supplies Lactulose Fresenius as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing and regulatory‑aligned distribution for healthcare providers. The product complies with EU pharmacopeial standards and is manufactured under GMP conditions.

Lactulose is an osmotic laxative used to manage conditions related to bowel motility and ammonia accumulation. - Constipation: softens stool and facilitates regular bowel movements. - Hepatic encephalopathy: reduces intestinal ammonia absorption, improving neurological status. - Hyperammonemia in liver disease: assists in lowering blood ammonia levels.

Lactulose may cause several adverse reactions, most of which are related to its laxative action and metabolic effects. Common Side Effects: - Diarrhea - Abdominal cramping - Flatulence - Nausea Serious or Rare Side Effects: - Severe dehydration - Electrolyte disturbances such as hypokalemia

When prescribing Lactulose Fresenius, clinicians should consider several safety measures. - Dose titration: adjust the dose based on stool frequency and individual response. - Fluid intake: maintain adequate hydration to prevent dehydration. - Electrolyte monitoring: watch for hypokalemia, especially in elderly or renal‑impaired patients. - Avoid in intestinal obstruction: risk of perforation and worsening obstruction. - Pregnancy and lactation: use only if clearly needed, as safety data are limited. Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Lactulose can interact with other medicines, requiring attention to avoid reduced efficacy or adverse effects. Major Interactions (Avoid): - Antibiotics such as neomycin or rifaximin: may diminish lactulose's effect by altering gut flora. - Other laxatives (e.g., senna, bisacodyl): additive laxative action can cause severe diarrhea. - Mineral supplements (e.g., magnesium, calcium carbonate): increase risk of electrolyte imbalance. Moderate Interactions (Monitor Closely): - Diuretics: monitor potassium levels due to potential additive hypokalemia. - Insulin or oral hypoglycemics: monitor blood glucose as lactulose may affect carbohydrate absorption.