GNH USA

Europe — EMA

Vivotif

Vivotif is an oral typhoid vaccine containing the live, attenuated Salmonella Typhi strain Ty21a. It helps protect against typhoid fever caused by Salmonella Ty

Salmonella Typhi, Strain Ty21a (Live, Attenuated)

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What is Salmonella Typhi, Strain Ty21a (Live, Attenuated)?

Vivotif is an oral typhoid vaccine containing the live, attenuated Salmonella Typhi strain Ty21a. It helps protect against typhoid fever caused by Salmonella Typhi bacteria. This vaccine is taken as capsules for oral use. Suitable for travelers and those in high-risk areas.

What is Salmonella Typhi, Strain Ty21a (Live, Attenuated) used for?

Vivotif is used to prevent typhoid fever, a serious bacterial infection spread through contaminated food and water. It is recommended for travelers visiting regions where typhoid is common, as well as for household contacts of typhoid carriers. The vaccine stimulates the immune system to produce antibodies against Salmonella Typhi. It is not used to treat active typhoid infections.

What are the side effects of Salmonella Typhi, Strain Ty21a (Live, Attenuated)?

After taking Vivotif, the body’s immune system responds by recognizing the weakened Salmonella Typhi bacteria. This may lead to mild, temporary effects such as stomach discomfort or mild fever. Some people may experience a slight headache or fatigue. These effects are generally short-lived and indicate the vaccine is working.

What precautions apply to Salmonella Typhi, Strain Ty21a (Live, Attenuated)?

Store Vivotif in a refrigerator between 2°C and 8°C (35°F and 46°F) to maintain potency. Keep the vaccine in its original packaging until ready to use. Do not freeze or expose to high temperatures. Discard if the packaging is damaged or the capsules appear discolored. Always check the expiration date before use.

What does Salmonella Typhi, Strain Ty21a (Live, Attenuated) interact with?

Vivotif should not be taken with antibiotics, as they may reduce the vaccine’s effectiveness. Avoid consuming alcohol within 48 hours of vaccination, as it may interfere with the immune response. If you are taking other medications or have a weakened immune system, consult a healthcare provider before use. Live vaccines like Vivotif may interact with certain treatments.

Frequently asked questions

How is Vivotif taken?+
Vivotif is taken orally as capsules, typically on an empty stomach with a cold or lukewarm drink.
Who should not take Vivotif?+
People with weakened immune systems, acute febrile illness, or those on antibiotics should avoid Vivotif.
How long does Vivotif protection last?+
Protection from Vivotif typically lasts about 5–7 years, but a booster may be needed for continued protection.
Can Vivotif cause side effects?+
Mild side effects may include stomach discomfort, mild fever, or headache, which usually resolve quickly.
Is Vivotif safe for children?+
Vivotif is approved for children aged 6 years and older, but dosage and use should be guided by a healthcare provider.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Salmonella Typhi, Strain Ty21a (Live, Attenuated)
Route
Oral Use
Manufacturer
Bavarian Nordic A/S
Origin
EU

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