Migräne-Kranit (Phenazone)

Phenazone, the active ingredient in Migräne‑Kranit, is a pyrazolone (non‑opioid analgesic) presented as an oral dosage form for oral use. It treats migraine, headache and other pain conditions in adults.\n\nGNH India supplies Migräne‑Kranit as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Phenazone acts as an analgesic and antipyretic, providing relief in common pain‑related conditions.\n\nMigraine: reduces headache intensity and associated symptoms.\nHeadache: alleviates tension‑type and other primary headaches.\nPain: provides symptomatic relief for mild to moderate musculoskeletal and dental pain.

Phenazone may cause a range of adverse reactions, most of which are mild and reversible.\n\nCommon Side Effects:\n- Nausea or upset stomach\n- Dizziness or light‑headedness\n- Skin rash or mild itching\n- Elevated liver enzymes (asymptomatic)\n- Mild headache\n\nSerious or Rare Side Effects:\n- Severe allergic reactions (anaphylaxis, angioedema)\n- Blood dyscrasias such as agranulocytosis or aplastic anemia\n- Hepatotoxicity with jaundice\n- Renal impairment in susceptible individuals\n- Stevens‑Johnson syndrome or toxic epidermal necrolysis

Phenazone should be used with caution in specific clinical situations.\n\nPregnancy: safety not established; avoid unless clearly needed.\nBreastfeeding: unknown excretion; consider risk‑benefit.\nRenal or hepatic impairment: dose adjustment may be required.\nHistory of hypersensitivity to pyrazolones: contraindicated.\nStore at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Phenazone can influence the activity of several co‑administered medicines.\n\nMajor Interactions (Avoid):\n- Anticoagulants (e.g., warfarin): increased bleeding risk.\n- Other non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened gastrointestinal toxicity.\n\nModerate Interactions (Monitor Closely):\n- Diuretics: possible reduction in diuretic efficacy.\n- Methotrexate: enhanced toxicity.\n- Lithium: altered serum levels.