Paracetamol 500 Mg Tablets (Paracetamol Ph. Eur.)

Paracetamol, the active ingredient in Paracetamol 500 Mg Tablets, is an analgesic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children when appropriate.

GNH USA supplies Paracetamol 500 Mg Tablets as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paracetamol is an analgesic and antipyretic that acts on common pain‑related pathways and fever mechanisms. - Headache: provides relief from tension‑type and mild migraine pain. - Fever: lowers elevated body temperature in infectious or inflammatory states. - Musculoskeletal pain: eases aches associated with back strain, sprains and minor joint discomfort. - Dental pain: reduces pain following dental procedures or toothache. - Menstrual discomfort: helps alleviate mild dysmenorrhoeic cramps.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset may be reported. - Skin rash: occasional mild erythema or itching. - Elevated liver enzymes: transient increase detected in blood tests.

Serious or Rare Side Effects: - Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention. - Hepatotoxicity: liver injury, especially with overdose or chronic high‑dose use. - Anaphylaxis: rare allergic reaction with symptoms such as swelling, difficulty breathing or hives.

Paracetamol should be used with awareness of potential risks and specific patient factors. - Liver disease: avoid or limit use; monitor hepatic function. - Alcohol use: limit intake as combined use increases hepatotoxic risk. - Pregnancy: use only under medical advice, especially in the third trimester. - Age extremes: dose adjustment may be required for very young children and the elderly. - Concomitant medications: review other products containing paracetamol to prevent accidental overdose. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Paracetamol may interact with several medicines, requiring attention to dosage and monitoring.

Major Interactions (Avoid): - Warfarin: increased anticoagulant effect may raise bleeding risk. - Isoniazid: combined use can enhance hepatotoxic potential.

Moderate Interactions (Monitor Closely): - Antiepileptics (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels. - Rifampicin: may increase hepatic metabolism, lowering efficacy. - Oral contraceptives: may slightly increase hepatotoxic risk. - High‑dose NSAIDs: additive liver stress when used together.