Paracetamol 1000mg Tablets (Paracetamol Ph. Eur.)

Paracetamol, the active ingredient in Paracetamol 1000mg Tablets, is an analgesic presented as a 1000 mg tablet for oral use. It treats pain and fever in adults and children when appropriate dosing is applied.

GNH USA supplies Paracetamol 1000mg Tablets as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paracetamol is an analgesic and antipyretic that acts on common pain‑related pathways and fever mechanisms. - Headache: provides relief of mild to moderate headache pain. - Musculoskeletal pain: reduces discomfort from strains, sprains and low‑back pain. - Fever: lowers elevated body temperature associated with infection or inflammation.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset may be reported. - Skin rash: occasional mild dermatologic reaction. - Elevated liver enzymes: transient increase in laboratory values.

Serious or Rare Side Effects: - Hepatotoxicity: risk of liver injury with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction. - Anaphylaxis: extremely rare systemic allergic response. - Blood disorders: rare cases of thrombocytopenia or neutropenia.

Paracetamol should be used with awareness of specific safety considerations. - Dose limits: do not exceed the maximum daily amount recommended by a healthcare professional. - Liver disease: avoid use or adjust dose in patients with existing hepatic impairment. - Alcohol use: limit alcohol consumption while taking this medication. - Pregnancy and breastfeeding: consult a healthcare provider before use. - Store below 25°C: keep in the original packaging, protect from moisture and heat.

Paracetamol may interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Isoniazid: can raise risk of liver toxicity.

Moderate Interactions (Monitor Closely): - Antiepileptics (e.g., carbamazepine, phenytoin): may increase metabolism of paracetamol, lowering its effectiveness. - Rifampicin: may reduce plasma concentrations of paracetamol. - Oral contraceptives: may slightly increase hepatic metabolism of paracetamol.