GNH USA

Europe — EMA

Norgesic (Orphenadrine Citrate, Paracetamol)

GNH USA supplies Norgesic (Orphenadrine citrate and paracetamol), a central acting muscle relaxant and analgesic for acute musculoskeletal pain and spasm.

Orphenadrine Citrate, Paracetamol

Request sourcing

1
Pack/s

What is Orphenadrine Citrate, Paracetamol?

Orphenadrine citrate and paracetamol, the active ingredients in Norgesic, are a central acting muscle relaxant and an analgesic presented as oral tablets for oral use. They are used to relieve muscle‑spasm related pain and associated discomfort in adult patients.

GNH USA supplies Norgesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Orphenadrine Citrate, Paracetamol used for?

Norgesic combines a muscle relaxant and an analgesic and is indicated for conditions involving musculoskeletal pain and spasm.

- Acute musculoskeletal pain: reduces pain intensity and improves functional mobility. - Muscle spasm due to strains or sprains: relaxes skeletal muscles and eases discomfort. - Low back pain: alleviates spasm‑related tension and pain. - Post‑traumatic injury pain: provides analgesia while relaxing contracted muscles.

What are the side effects of Orphenadrine Citrate, Paracetamol?

Common side effects are generally mild and transient.

Common Side Effects: - Drowsiness: feeling unusually sleepy or fatigued. - Dry mouth: reduced salivation leading to throat discomfort. - Dizziness: light‑headed sensation, especially when standing quickly. - Nausea: mild stomach upset or urge to vomit.

Serious or Rare Side Effects: - Severe allergic reaction: rash, swelling, or difficulty breathing. - Hepatotoxicity: liver injury, particularly with excessive paracetamol exposure. - Cardiac arrhythmia: irregular heartbeat that may require medical attention.

What precautions apply to Orphenadrine Citrate, Paracetamol?

Before prescribing Norgesic, clinicians should consider several safety aspects.

- Liver function assessment: evaluate hepatic health due to paracetamol content. - Elderly patients: start with lower doses and monitor for increased sedation. - Glaucoma or urinary retention: use cautiously as anticholinergic effects may exacerbate these conditions. - Alcohol consumption: advise patients to limit alcohol to reduce liver risk. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

What does Orphenadrine Citrate, Paracetamol interact with?

Norgesic may interact with other medicines; awareness of interaction severity helps guide safe use.

Major Interactions (Avoid): - MAO inhibitors: risk of hypertensive crisis. - Other anticholinergics: increased anticholinergic burden. - CNS depressants (e.g., benzodiazepines, opioids): additive sedation and respiratory depression. - Alcohol: heightened liver toxicity and sedation.

Moderate Interactions (Monitor Closely): - Warfarin: possible alteration of anticoagulant effect. - Antihypertensive agents: may enhance blood‑pressure lowering. - Antihistamines: could increase drowsiness and anticholinergic side effects.

Frequently asked questions

What is Norgesic used for?+
Norgesic is a prescription oral tablet that combines orphenadrine citrate, a central muscle relaxant, with paracetamol, an analgesic. It is used to relieve pain and muscle spasm associated with acute musculoskeletal conditions such as strains, sprains, low‑back pain, and post‑traumatic injuries in adult patients.
How does orphenadrine citrate work in Norgesic?+
Orphenadrine citrate acts as an anticholinergic and central muscle relaxant, likely by blocking NMDA receptors and reducing neuronal excitability in the spinal cord. This action helps to relax skeletal muscles and decrease spasm‑related pain.
What is the usual dose of Norgesic?+
The specific dose of Norgesic is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and overall health. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Norgesic safe during pregnancy or breastfeeding?+
Safety data for Norgesic in pregnancy and lactation are limited. The prescriber should weigh potential benefits against risks, and it is generally recommended to avoid use unless clearly needed. Breastfeeding mothers should consult their doctor before taking the medication.
How do I order Norgesic from GNH USA?+
To order Norgesic, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.
How does Norgesic compare with other muscle relaxants?+
Norgesic combines a muscle relaxant (orphenadrine) with an analgesic (paracetamol), offering both spasm relief and pain control in a single tablet. Compared with single‑ingredient relaxants such as cyclobenzaprine, Norgesic may reduce the need for additional analgesics, but the choice depends on the patient’s specific clinical profile and tolerability.
What are the storage requirements for Norgesic?+
Norgesic tablets should be stored at room temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect from moisture and direct sunlight, and keep out of reach of children.
How is Norgesic administered?+
Norgesic is taken orally, usually with a full glass of water. The tablet should be swallowed whole and not chewed or crushed, unless the prescriber advises otherwise. It is typically taken with or without food as directed by the healthcare provider.
What are the most serious risks associated with Norgesic?+
Serious risks include severe allergic reactions (rash, swelling, breathing difficulty), hepatotoxicity from paracetamol overdose, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience any signs of these conditions.
Who should not use Norgesic?+
Norgesic should be avoided in patients with known hypersensitivity to orphenadrine, paracetamol, or any excipients, as well as in individuals with severe liver disease, uncontrolled glaucoma, or urinary retention. It is also contraindicated in patients taking monoamine oxidase inhibitors.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Orphenadrine Citrate, Paracetamol
Route
Oral Use
Manufacturer
Viatris Ab
Origin
EU

Related products

Norgesic

Norgesic

Orphenadrine Citrate, Paracetamol

Viatris Austria Gmbh
EU
Norgesic

Norgesic

Orphenadrine Citrate, Paracetamol

Viatris Oy
EU
Norgesic

Norgesic

Orphenadrine Citrate, Paracetamol

Viatris Healthcare Limited
EU
Norgesic

Norgesic

Orphenadrine Citrate, Paracetamol

Viatris Aps
EU