Natrio Jodidas [131i] Ge Healthcare (Sodium Iodide (131i))

Sodium Iodide, the active ingredient in Natrio Jodidas [131i] Ge Healthcare, is a radioactive iodine presented as a diagnostic radiopharmaceutical for oral use. It is selectively taken up by thyroid tissue, enabling imaging and functional assessment of the gland in patients with suspected thyroid disorders.

GNH USA supplies Natrio Jodidas [131i] Ge Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for cross‑border distribution.

Natrio Jodidas (Sodium Iodide) is used in nuclear medicine for diagnostic evaluation of thyroid‑related conditions. - Thyroid imaging: enables visualization of thyroid tissue to assess anatomy and function. - Hyperthyroidism assessment: helps determine the functional activity of overactive thyroid tissue. - Thyroid nodule evaluation: assists in distinguishing benign from malignant nodules through uptake patterns.

Adverse reactions may occur following oral administration of radioactive iodine.

Common Side Effects: - Nausea or vomiting. - Metallic taste in the mouth. - Mild abdominal discomfort. - Transient increase in thyroid hormone levels. - Temporary sore throat. - Mild skin erythema at the site of radiation exposure.

Serious or Rare Side Effects: - Radiation thyroiditis causing painful swelling. - Acute hypothyroidism requiring hormone replacement. - Bone marrow suppression leading to leukopenia. - Allergic reactions such as rash or urticaria. - Severe radiation burns if mishandled. - Long‑term risk of secondary malignancies (very rare).

Use of Natrio Jodidas requires careful consideration of patient factors and handling procedures. - Pregnancy: avoid unless clearly indicated, as fetal thyroid can be affected. - Breastfeeding: discontinue breastfeeding for an appropriate period after administration. - Thyroid function: assess baseline thyroid status before use. - Concomitant iodine exposure: avoid iodine‑containing contrast agents or supplements for several days prior. - Renal impairment: monitor because excretion is renal. - Store at ambient temperature: keep below 25°C in the original container, protect from moisture and light.

Radioactive iodine can interact with several medications and substances that affect iodine uptake.

Major Interactions (Avoid): - Antithyroid drugs (e.g., methimazole, propylthiouracil): markedly reduce iodine uptake. - Iodine‑containing contrast agents: block thyroid uptake for up to several weeks. - High‑dose potassium iodide supplements: competitively inhibit tracer accumulation.

Moderate Interactions (Monitor Closely): - Thyroid hormone replacement therapy: may alter diagnostic interpretation. - Lithium therapy: can increase iodine retention in the thyroid. - Amiodarone: high iodine load may affect imaging results. - Diuretics: may influence renal clearance of the isotope.