Natrii Iodidum [131i] Ge Healthcare (Sodium Iodide (131i))

Sodium Iodide, the active ingredient in Natrii Iodidum [131i] Ge Healthcare, is a radioactive iodine presented as an oral formulation for diagnostic and therapeutic use in thyroid conditions. It is taken up by thyroid tissue and emits radiation that can be visualized or used to ablate abnormal cells. GNH USA supplies Natrii Iodidum [131i] Ge Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and pharmacies worldwide.

Natrii Iodidum [131i] is employed in the management of thyroid‑related disorders, providing both imaging and therapeutic capabilities. - Thyroid imaging: enables visualization of thyroid tissue for diagnostic assessment. - Hyperthyroidism treatment: delivers targeted radiation to reduce excess thyroid hormone production. - Thyroid cancer therapy: provides ablative radiation to residual thyroid tissue after surgery.

Adverse reactions may occur following administration of radioactive iodine.

Common Side Effects: - Nausea or mild gastrointestinal upset. - Transient neck discomfort or tenderness. - Altered taste sensation. - Temporary hypothyroidism. - Mild leukopenia. - Fatigue.

Serious or Rare Side Effects: - Severe hypothyroidism requiring hormone replacement. - Radiation thyroiditis with pain and swelling. - Bone marrow suppression leading to pancytopenia. - Allergic reaction or anaphylaxis. - Pulmonary fibrosis (very rare).

Prior to use, several safety considerations should be observed. - Pregnancy: avoid unless clearly indicated, as fetal thyroid can be affected. - Breastfeeding: contraindicated because iodine may be secreted in milk. - Renal impairment: monitor renal function as excretion may be altered. - Baseline thyroid function: assess and monitor post‑administration levels. - Radiation safety: follow institutional protocols to limit exposure to staff and public. Store at ambient temperature: keep in original container, protect from light and moisture.

Radioactive iodine can interact with other medications that affect iodine uptake or thyroid function.

Major Interactions (Avoid): - Thyroid hormone replacement: may reduce efficacy of radioactive iodine. - Antithyroid drugs (methimazole, propylthiouracil): block iodine uptake, should not be co‑administered. - Lithium: interferes with iodine uptake, avoid concurrent use.

Moderate Interactions (Monitor Closely): - Amiodarone: high iodine load may affect uptake, monitor thyroid function. - Corticosteroids: may modify inflammatory response, monitor patient. - Diuretics: can affect renal clearance of iodine, monitor renal parameters.