GNH USA

Europe — EMA

Metoprololtartrat Al (Metoprolol Tartrate Ph. Eur.)

GNH USA supplies Metoprololtartrat Al (Metoprolol Tartrate), a beta blocker for hypertension, angina and heart failure. Request a quote for global supply.

Metoprolol Tartrate Ph. Eur.

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What is Metoprolol Tartrate Ph. Eur.?

Metoprolol tartrate, the active ingredient in Metoprololtartrat Al, is a beta blocker presented as an oral tablet for oral use. It lowers blood pressure and heart rate, reducing cardiac workload in patients with hypertension, angina, heart failure, and other cardiovascular conditions.

GNH USA supplies Metoprololtartrat Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution.

What is Metoprolol Tartrate Ph. Eur. used for?

Metoprolol tartrate is used to manage several cardiovascular disorders by modulating beta‑adrenergic activity.

- Hypertension: reduces systolic and diastolic pressure to lower cardiovascular risk. - Angina pectoris: decreases myocardial oxygen demand, relieving chest pain. - Heart failure: improves ventricular function and reduces hospitalisation rates. - Post‑myocardial infarction prophylaxis: lowers the chance of recurrent cardiac events. - Cardiac arrhythmias: stabilises heart rhythm by slowing conduction through the AV node.

What are the side effects of Metoprolol Tartrate Ph. Eur.?

Metoprolol tartrate may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Fatigue or general weakness - Dizziness or light‑headedness - Cold extremities (hands and feet) - Bradycardia (slow heart rate) - Gastrointestinal upset (nausea, abdominal discomfort) - Sleep disturbances (insomnia or vivid dreams)

Serious or Rare Side Effects: - Severe bradycardia or heart block - Marked hypotension - Bronchospasm, especially in patients with asthma or COPD - Depression or mood changes - Allergic reactions (rash, angioedema, anaphylaxis) - Cardiogenic shock in extreme cases

What precautions apply to Metoprolol Tartrate Ph. Eur.?

Before initiating therapy, consider the following precautions.

- Dose adjustment in renal impairment: reduce dose according to renal function. - Monitor heart rate and blood pressure: check regularly during initiation and dose changes. - Avoid abrupt discontinuation: taper under medical supervision to prevent rebound hypertension. - Caution in asthma or COPD: may exacerbate bronchospasm. - Store at below 25°C: keep in the original container, protect from moisture.

What does Metoprolol Tartrate Ph. Eur. interact with?

Metoprolol tartrate can interact with several drug classes; awareness helps minimise risk.

Major Interactions (Avoid): - Concomitant use with non‑selective beta blockers: additive bradycardia. - Combination with calcium‑channel blockers (verapamil, diltiazem): risk of severe AV block. - Concurrent use with potent CYP2D6 inhibitors (e.g., quinidine, paroxetine): may increase plasma levels.

Moderate Interactions (Monitor Closely): - Co‑administration with diuretics: may enhance hypotensive effect. - Use with antidiabetic agents: may mask hypoglycaemia symptoms. - Interaction with NSAIDs: may reduce antihypertensive efficacy.

Frequently asked questions

What is Metoprololtartrat Al used for?+
Metoprololtartrat Al contains metoprolol tartrate, a beta‑adrenergic blocking agent indicated for the treatment of hypertension, angina pectoris, chronic heart failure, post‑myocardial infarction prophylaxis, and certain cardiac arrhythmias. It helps control blood pressure and heart rate, reducing the workload on the heart.
How does Metoprolol tartrate work?+
Metoprolol tartrate selectively antagonises β1‑adrenergic receptors in cardiac tissue. By blocking these receptors, it reduces sympathetic stimulation, leading to a slower heart rate, decreased myocardial contractility, and lower cardiac output, which together lower arterial pressure and myocardial oxygen demand.
What is the usual dose of Metoprololtartrat Al?+
The appropriate dose of Metoprololtartrat Al is determined by a qualified prescriber based on the patient’s clinical condition, response to therapy, and any comorbidities. Dosage may be adjusted during treatment to achieve optimal blood pressure or heart‑rate control.
Is Metoprololtartrat Al safe during pregnancy or breastfeeding?+
Data on the safety of metoprolol tartrate in pregnancy and lactation are limited. It is generally classified as a drug to be used only if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.
How do I order Metoprololtartrat Al from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.
How does Metoprolol compare with other beta blockers?+
Metoprolol is a cardio‑selective (β1‑selective) beta blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. It is commonly preferred for patients with respiratory disease who still require beta‑blockade. Its pharmacokinetic profile allows once‑ or twice‑daily dosing, whereas some alternatives may require more frequent administration.
How should Metoprololtartrat Al be stored?+
Store Metoprololtartrat Al at temperatures below 25 °C, in the original packaging, and protect it from moisture and direct sunlight. Do not store in a location where temperature may exceed the recommended range, as this could affect product stability.
How is Metoprololtartrat Al administered?+
Metoprololtartrat Al is taken orally, usually with or without food, as directed by the prescribing clinician. Tablets should be swallowed whole with a glass of water. The exact timing (e.g., morning or evening) and frequency depend on the individual treatment plan.
What are the most serious risks to watch for while taking Metoprololtartrat Al?+
Serious adverse events include severe bradycardia, marked hypotension, heart block, bronchospasm in patients with asthma or COPD, and allergic reactions such as rash or anaphylaxis. Patients should seek immediate medical attention if they experience fainting, chest pain, severe shortness of breath, or signs of an allergic reaction.
Who should not use Metoprololtartrat Al?+
Metoprololtartrat Al is contraindicated in patients with known hypersensitivity to metoprolol or any excipients, those with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, cardiogenic shock, and uncontrolled heart failure. Caution is also advised for individuals with severe asthma, chronic obstructive pulmonary disease, or significant peripheral vascular disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metoprolol Tartrate Ph. Eur.
Route
Oral Use
Manufacturer
Aliud Pharma Gmbh
Origin
EU

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