GNH USA

Europe — EMA

Metoprolol 1 A Pharma (Metoprolol Tartrate Ph. Eur.)

GNH USA supplies Metoprolol 1 A Pharma (Metoprolol), a beta blocker for hypertension, angina and heart failure. Request a quote for global supply.

Metoprolol Tartrate Ph. Eur.

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What is Metoprolol Tartrate Ph. Eur.?

Metoprolol tartrate, the active ingredient in Metoprolol 1 A Pharma, is a beta blocker presented as an oral tablet for oral use. It is employed to lower blood pressure, relieve angina and improve outcomes in heart failure and post‑myocardial infarction patients. GNH USA supplies Metoprolol 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metoprolol Tartrate Ph. Eur. used for?

Metoprolol tartrate is a selective β1‑adrenergic antagonist used in several cardiovascular conditions. - Hypertension: reduces systolic and diastolic pressure by decreasing cardiac output. - Angina pectoris: lowers myocardial oxygen demand, relieving chest pain. - Post‑myocardial infarction: improves survival by limiting arrhythmias and remodeling. - Chronic heart failure: enhances ventricular function and reduces hospitalisation. - Cardiac arrhythmias: controls ventricular rate in atrial fibrillation and other supraventricular tachyarrhythmias.

What are the side effects of Metoprolol Tartrate Ph. Eur.?

Metoprolol tartrate may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Fatigue: feeling unusually tired or weak. - Dizziness or light‑headedness, especially on standing. - Cold extremities: reduced peripheral circulation. - Bradycardia: slower than normal heart rate. - Gastrointestinal upset: nausea, abdominal discomfort. - Headache: mild to moderate intensity.

Serious or Rare Side Effects: - Bronchospasm: difficulty breathing, particularly in asthmatic patients. - Severe bradycardia or heart block requiring medical attention. - Marked hypotension: sudden drop in blood pressure. - Allergic reactions: rash, itching, swelling, or anaphylaxis. - Depression or mood changes. - Worsening heart failure symptoms.

What precautions apply to Metoprolol Tartrate Ph. Eur.?

Before prescribing Metoprolol tartrate, clinicians should consider several safety measures. - Assess cardiovascular status: evaluate heart rate and blood pressure prior to initiation. - Monitor for bronchospastic disease: avoid or use with caution in uncontrolled asthma or COPD. - Adjust in renal impairment: dose may need modification in reduced kidney function. - Caution in diabetes: beta‑blockade can mask hypoglycaemia symptoms. - Avoid abrupt discontinuation: taper gradually to prevent rebound tachycardia. - Store at ambient temperature: keep below 25°C, protect from moisture and light.

What does Metoprolol Tartrate Ph. Eur. interact with?

Metoprolol tartrate can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid): - Other AV‑nodal blockers (e.g., verapamil, diltiazem): may cause severe bradycardia. - Potent CYP2D6 inhibitors (e.g., quinidine, propafenone): increase plasma metoprolol levels. - Insulin or sulfonylureas: beta‑blockade may mask hypoglycaemia signs.

Moderate Interactions (Monitor Closely): - NSAIDs: may blunt antihypertensive effect. - SSRIs or other antidepressants: can enhance bradycardia risk. - Thyroid hormones: may alter heart‑rate response, requiring dose adjustment.

Frequently asked questions

What conditions is Metoprolol 1 A Pharma used for?+
Metoprolol 1 A Pharma is prescribed to manage high blood pressure, relieve chest pain from angina, improve outcomes after a heart attack, treat chronic heart failure, and control heart rate in certain cardiac arrhythmias such as atrial fibrillation.
How does Metoprolol tartrate work in the body?+
Metoprolol tartrate selectively blocks β1‑adrenergic receptors in the heart, reducing the effects of adrenaline and noradrenaline. This lowers heart rate, contractility, and conduction speed, which together decrease cardiac output and myocardial oxygen demand, helping to control blood pressure and reduce ischemic stress.
What is the usual dose of Metoprolol 1 A Pharma?+
The appropriate dose of Metoprolol 1 A Pharma is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the dosage instructions provided by their healthcare professional and not adjust the dose on their own.
Is Metoprolol 1 A Pharma safe during pregnancy or breastfeeding?+
Safety data for Metoprolol during pregnancy and lactation are limited. The medication should only be used if the potential benefits justify any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.
How do I order Metoprolol 1 A Pharma from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Metoprolol compare with other beta blockers?+
Metoprolol is a cardio‑selective (β1‑selective) beta blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. It is commonly chosen for patients with respiratory concerns, whereas non‑selective blockers may be preferred when broader β‑receptor coverage is needed.
What are the storage requirements for Metoprolol 1 A Pharma?+
Metoprolol 1 A Pharma should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from excess moisture, heat, and direct sunlight to maintain stability.
How is Metoprolol 1 A Pharma administered?+
Metoprolol 1 A Pharma is taken orally, usually with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.
What are the most serious risks associated with Metoprolol 1 A Pharma?+
Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in susceptible individuals, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience symptoms like fainting, severe shortness of breath, or swelling of the face and throat.
Who should not use Metoprolol 1 A Pharma?+
Metoprolol 1 A Pharma is contraindicated in patients with known hypersensitivity to metoprolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, and individuals with uncompensated heart failure or severe asthma/COPD where β‑blockade could worsen airway obstruction.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metoprolol Tartrate Ph. Eur.
Route
Oral Use
Manufacturer
1 A Pharma Gmbh
Origin
EU

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