Menadion Scanpharm

Phytomenadione, the active ingredient in Menadion Scanpharm, is a Vitamin K presented as an oral preparation for use in patients requiring correction of vitamin K deficiency or reversal of anticoagulant‑induced bleeding. It acts as a hemostasis agent by supporting the activation of clotting factors II, VII, IX and X, thereby helping to restore normal coagulation.

GNH USA supplies Menadion Scanpharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Menadion Scanpharm provides vitamin K activity for disorders of coagulation and related therapeutic pathways. - Vitamin K deficiency: restores normal clotting factor activation and reduces bleeding risk. - Anticoagulant‑related bleeding: reverses excess anticoagulation to control hemorrhage. - Pre‑surgical preparation: ensures adequate coagulation status before invasive procedures.

Adverse reactions may occur with oral vitamin K preparations.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Vomiting: occasional emesis. - Diarrhea: loose stools. - Abdominal pain: discomfort in the stomach area. - Headache: transient cranial pain. - Rash: mild skin irritation.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Severe hypersensitivity: swelling, itching, or difficulty breathing. - Thrombosis: unexpected clot formation. - Hemolysis: breakdown of red blood cells. - Elevated liver enzymes: indication of hepatic stress. - Stevens‑Johnson syndrome: rare severe skin reaction.

When prescribing Menadion Scanpharm, clinicians should consider several safety measures. - Dose adjustment in liver disease: monitor hepatic function and modify dose if needed. - Monitor coagulation parameters: check INR or PT regularly during therapy. - Avoid in patients with known hypersensitivity: discontinue if allergic reaction occurs. - Caution with concurrent warfarin: vitamin K may diminish anticoagulant effect. - Pregnancy considerations: safety not established; use only if benefit outweighs risk. - Store at ambient temperature: keep in the original pack, protect from moisture.

Phytomenadione may interact with several medicines, requiring attention to the level of interaction.

Major Interactions (Avoid): - Warfarin: may reduce anticoagulant effect and destabilize INR control. - Broad‑spectrum antibiotics (e.g., cephalosporins): can impair gut flora synthesis of vitamin K, altering efficacy. - Bile acid sequestrants (e.g., cholestyramine): may decrease oral absorption of vitamin K.

Moderate Interactions (Monitor Closely): - Vitamin E supplements: potential interference with clotting mechanisms. - Heparin: additive anticoagulant effect may increase bleeding risk. - Other vitamin K‑containing products: concurrent use may lead to excess vitamin K activity.