GNH USA

Europe — EMA

Ka-Vit Tropfen

GNH USA supplies Ka-Vit Tropfen (Phytomenadione), a Vitamin K hemostatic agent for vitamin K deficiency, newborn hemorrhage prevention, and anticoagulant

Phytomenadione

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What is Phytomenadione?

Phytomenadione, the active ingredient in Ka-Vit Tropfen, is a Vitamin K presented as oral drops for oral use. It supports normal blood clotting by addressing vitamin K deficiency and is employed in newborns to prevent hemorrhage and in patients requiring reversal of oral anticoagulant therapy.

GNH USA supplies Ka-Vit Tropfen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution. Customers benefit from reliable logistics, temperature-controlled shipping where required, and responsive technical support.

What is Phytomenadione used for?

Ka-Vit Tropfen (phytomenadione) is used to correct impaired coagulation associated with vitamin K–dependent pathways.

- Vitamin K deficiency: restores activity of clotting factors II, VII, IX and X. - Newborn hemorrhage prevention: provides prophylactic vitamin K to reduce risk of bleeding in infants. - Reversal of oral anticoagulant therapy: counteracts the effect of warfarin and similar agents to re‑establish normal clotting.

What are the side effects of Phytomenadione?

Adverse reactions may occur with oral vitamin K administration.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Vomiting: occasional emesis after dosing. - Diarrhea: loose stools in some patients. - Abdominal pain: transient discomfort. - Headache: mild tension‑type headache. - Skin rash: mild erythema or pruritus.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Hemolysis: rare destruction of red blood cells. - Elevated liver enzymes: possible hepatic irritation. - Thrombosis: uncommon formation of abnormal clots. - Severe hypersensitivity: including angioedema. - Hyperbilirubinemia: rare increase in bilirubin levels.

What precautions apply to Phytomenadione?

Before using Ka-Vit Tropfen, consider the following precautions.

- Pregnancy: safety not established; use only if potential benefit justifies the risk. - Breastfeeding: unknown excretion in milk; evaluate risk versus benefit. - Renal impairment: monitor clotting status closely. - Concomitant anticoagulants: may reduce anticoagulant efficacy; adjust therapy as needed. - Bleeding disorders: assess baseline coagulation before administration. - Store at ambient temperature: keep in the original container, protect from moisture and light.

What does Phytomenadione interact with?

Phytomenadione may interact with several medicines.

Major Interactions (Avoid): - Warfarin: antagonizes anticoagulant effect, potentially leading to clotting. - Broad‑spectrum antibiotics (e.g., cephalosporins): reduce intestinal vitamin K synthesis, diminishing efficacy. - Bile‑acid sequestrants: decrease absorption of oral vitamin K.

Moderate Interactions (Monitor Closely): - Vitamin K supplements: may alter therapeutic response. - Heparin: additive effect on clotting parameters. - Oral contraceptives: possible increased risk of thrombosis when combined with high vitamin K levels.

Frequently asked questions

What is Ka‑Vit Tropfen used for?+
Ka‑Vit Tropfen contains phytomenadione, a form of vitamin K, and is used to treat vitamin K deficiency, prevent bleeding in newborns, and reverse the anticoagulant effects of oral agents such as warfarin. It helps restore normal clotting factor activity in these clinical situations.
How does phytomenadione work?+
Phytomenadione serves as a cofactor for the gamma‑carboxylation of specific clotting factors (II, VII, IX, X) in the liver. This biochemical step enables the factors to bind calcium, which is essential for the formation of a stable fibrin clot and normal hemostasis.
What is the usual dose of Ka‑Vit Tropfen?+
The dose of Ka‑Vit Tropfen is individualized and determined by a qualified prescriber based on the patient’s age, clinical condition, and laboratory results. Healthcare professionals calculate the appropriate amount and frequency to achieve the desired therapeutic effect.
Is Ka‑Vit Tropfen safe during pregnancy or breastfeeding?+
Safety data for phytomenadione in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother or infant outweighs any possible risk, and the decision should be made by a healthcare provider.
How do I order Ka‑Vit Tropfen from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ka‑Vit Tropfen compare with other vitamin K products?+
Ka‑Vit Tropfen is an oral liquid formulation of phytomenadione, whereas many alternatives are available as injectable phytonadione or synthetic vitamin K analogues. Oral drops offer ease of administration, especially for infants and patients with needle aversion, but may have slower onset compared with parenteral preparations.
What are the storage and handling requirements for Ka‑Vit Tropfen?+
Store Ka‑Vit Tropfen at ambient temperature, preferably below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from moisture and direct sunlight, and avoid freezing. Check the label for any specific expiry information before use.
How is Ka‑Vit Tropfen administered?+
Ka‑Vit Tropfen is administered orally using the calibrated dropper provided with the product. The prescribed number of drops is measured directly into the mouth or mixed with a small amount of food or liquid, as directed by the prescribing clinician.
What are the most serious risks associated with Ka‑Vit Tropfen?+
Serious adverse reactions, although rare, include anaphylaxis, severe hypersensitivity, hemolysis, thrombosis, and significant liver enzyme elevations. Patients should be monitored for signs of allergic reaction, unexpected clot formation, or abnormal bleeding and seek immediate medical attention if these occur.
Who should not use Ka‑Vit Tropfen?+
Ka‑Vit Tropfen should be avoided in individuals with known hypersensitivity to phytomenadione or any excipients in the formulation. It is also contraindicated in patients with documented severe vitamin K toxicity or those for whom vitamin K supplementation is medically inappropriate, as determined by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phytomenadione
Route
Oral Use
Manufacturer
Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim
Origin
EU

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