Lidoproctene

Hydrocortisone acetate, the active ingredient in Lidoproctene, is a corticosteroid presented as a rectal formulation for local use. It reduces inflammation and provides analgesia in patients with hemorrhoidal disease, anal fissures, proctitis, and related rectal discomfort.

GNH USA supplies Lidoproctene as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established distribution channels across Europe, Asia, Africa and the Americas.

Lidoproctene combines a corticosteroid and a local anesthetic to address inflammatory and painful conditions of the rectal mucosa.

- Hemorrhoids: reduces swelling, pain and itching associated with hemorrhoidal tissue. - Anal fissures: promotes healing and alleviates severe anal pain. - Proctitis: diminishes inflammation of the rectal lining. - Rectal pain: provides rapid local analgesia. - Itching: relieves pruritus caused by irritation or inflammation.

Topical application of Lidoproctene may be associated with local and systemic adverse reactions.

Common Side Effects: - Mild burning sensation: transient discomfort at the application site. - Local irritation: redness or mild inflammation. - Pruritus: occasional itching after use. - Dryness: skin dryness around the rectal area. - Stinging: brief sharp sensation upon insertion.

Serious or Rare Side Effects: - Allergic reaction: rash, swelling, or hives indicating hypersensitivity. - Anaphylaxis: rare systemic allergic response requiring emergency care. - Severe skin necrosis: extensive tissue damage at the site. - Systemic corticosteroid effects: adrenal suppression with prolonged use. - Methemoglobinemia: rare blood disorder linked to lidocaine absorption.

Before using Lidoproctene, consider the following precautions to ensure safe and effective therapy.

- Pregnancy: avoid unless clearly needed; consult a healthcare professional. - Breastfeeding: potential transfer to infant; discuss risks with a physician. - Prolonged use: limit duration to reduce risk of systemic corticosteroid absorption. - Infections: do not apply to areas with bacterial, fungal or viral infection without medical advice. - Children: safety not established; use only under pediatric supervision. - Store at room temperature: keep in the original packaging, protect from moisture and light.

Lidoproctene may interact with other medicines; awareness of significant interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - Systemic corticosteroids: concurrent use can increase risk of adrenal suppression. - Amiodarone or other class I antiarrhythmics: may enhance lidocaine toxicity. - MAO inhibitors: potential for increased systemic effects of lidocaine.

Moderate Interactions (Monitor Closely): - Anticoagulants (e.g., warfarin): local irritation may increase bleeding risk. - Antidiabetic agents: corticosteroid absorption could affect glucose control. - Other topical anesthetics: additive local anesthetic effect may cause numbness. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): combined anti‑inflammatory action may mask infection signs.