Lidoproctene

Hydrocortisone acetate and lidocaine hydrochloride, the active ingredients in Lidoproctene, are a corticosteroid and a local anesthetic presented as a rectal formulation for topical use. The combination reduces inflammation and provides analgesia in patients with hemorrhoidal disease, anal fissures, and proctitis.

GNH USA supplies Lidoproctene as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for import and distribution. Customers benefit from reliable logistics, batch traceability, and responsive technical support.

Lidoproctene acts locally on the anorectal mucosa to relieve inflammation and pain associated with common proctologic conditions. - Hemorrhoids: reduces swelling and discomfort, facilitating symptom relief. - Anal fissure: promotes healing by decreasing inflammation and providing analgesia. - Proctitis: alleviates mucosal inflammation and associated pain.

Lidoproctene may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Burning or stinging sensation. - Itching or mild irritation. - Minor rectal bleeding.

Serious or Rare Side Effects: - Allergic reaction with rash, swelling, or urticaria. - Severe ulceration or tissue necrosis. - Systemic corticosteroid effects such as adrenal suppression (rare).

Before using Lidoproctene, consider the following precautions to ensure safe and effective therapy. - Avoid prolonged use: limit treatment duration to the period prescribed by a healthcare professional. - Do not apply to infected or ulcerated tissue: assess the area before administration. - Monitor blood glucose: corticosteroid absorption may affect diabetic patients. - Use with caution in patients with known hypersensitivity to corticosteroids or local anesthetics. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Lidoproctene can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - Systemic corticosteroids: additive immunosuppression may increase infection risk. - Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise systemic exposure to hydrocortisone acetate.

Moderate Interactions (Monitor Closely): - Anticoagulants (e.g., warfarin): local irritation may enhance bleeding tendency. - Antidiabetic agents: corticosteroid absorption can elevate blood glucose levels. - Other topical anesthetics: cumulative local anesthetic toxicity.