GNH USA

Europe — EMA

Lacydyna (Lacidipine)

GNH USA supplies Lacydyna (Lacidipine), a dihydropyridine calcium channel blocker for hypertension. Request a quote for global supply to providers worldwide.

Lacidipine

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What is Lacidipine?

Lacidipine, the active ingredient in Lacydyna, is a dihydropyridine calcium channel blocker presented as a tablet for oral use. It works by relaxing vascular smooth muscle, thereby reducing systemic vascular resistance and lowering elevated blood pressure in adult patients diagnosed with hypertension.

GNH USA supplies Lacydyna as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to quality‑assured medicines for healthcare providers across multiple markets. The company adheres to stringent quality standards and offers global logistics support to ensure timely delivery.

What is Lacidipine used for?

Lacydyna, a dihydropyridine calcium channel blocker, is indicated for conditions related to high blood pressure.

Hypertension: reduces systolic and diastolic blood pressure, helping to achieve target levels in adult patients.

What are the side effects of Lacidipine?

Lacidipine may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Headache: mild to moderate headache often reported. - Flushing: transient warmth and redness of the skin. - Dizziness: light‑headed sensation, especially after standing. - Peripheral edema: swelling of ankles or feet. - Tachycardia: increased heart rate. - Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure causing faintness. - Myocardial infarction: rare occurrence of heart attack. - Angina: chest pain due to reduced coronary flow. - Hepatic dysfunction: abnormal liver enzymes or hepatitis. - Allergic reactions: rash, pruritus, or anaphylaxis. - Arrhythmias: irregular heart rhythms.

What precautions apply to Lacidipine?

Before prescribing Lacydyna, clinicians should consider several precautionary measures to ensure safe use. - Blood pressure monitoring: check baseline and periodic readings to avoid excessive lowering. - Cardiovascular status: avoid in patients with unstable angina or recent myocardial infarction. - Liver function: assess hepatic impairment, as metabolism may be altered. - Drug interactions: review concomitant CYP3A4 inhibitors or inducers. - Pregnancy and lactation: use only if benefits outweigh potential risks. - Store at ambient temperature: keep in the original pack, protect from moisture and light.

What does Lacidipine interact with?

Lacidipine can interact with other medicines, influencing its effectiveness or safety.

Major Interactions (Avoid): - CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase lacidipine plasma concentrations. - Grapefruit juice: can markedly raise drug levels, leading to hypotension. - Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce therapeutic effect.

Moderate Interactions (Monitor Closely): - Other antihypertensives: additive blood pressure lowering may require dose adjustment. - Diuretics: combined use can increase risk of electrolyte disturbances. - Beta‑blockers: monitor for excessive bradycardia or AV block.

Frequently asked questions

What is Lacydyna used for?+
Lacydyna contains lacidipine, a dihydropyridine calcium channel blocker that is prescribed to lower elevated blood pressure in adults diagnosed with hypertension. By reducing systemic vascular resistance, it helps patients achieve and maintain target blood pressure levels, thereby decreasing the risk of cardiovascular complications associated with uncontrolled hypertension.
How does lacidipine work?+
Lacidipine selectively blocks L‑type calcium channels on vascular smooth‑muscle cells. This inhibition prevents calcium entry that is necessary for muscle contraction, causing relaxation of arterial smooth muscle and vasodilation. The resulting fall in peripheral resistance lowers arterial pressure without markedly affecting heart rate or contractility, providing an effective antihypertensive effect.
What is the usual dose of Lacydyna?+
The appropriate dose of Lacydyna is individualized by the prescribing healthcare professional based on the patient’s blood pressure, response to therapy, and any concomitant medications. Dosage adjustments are made according to clinical judgment, and patients should follow the prescriber’s instructions without altering the regimen on their own.
Is Lacydyna safe during pregnancy or breastfeeding?+
Safety data for lacidipine in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers typically consider alternative antihypertensives with more established safety profiles for pregnant or nursing women.
How do I order Lacydyna from GNH USA?+
To request Lacydyna, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, and will ask for trade or institutional credentials. The sales team then provides pricing, availability, shipping details (including any cold‑chain requirements), and assists with import documentation.
How does Lacydyna compare with amlodipine?+
Both lacidipine and amlodipine belong to the dihydropyridine calcium channel blocker class and lower blood pressure by vasodilation. Lacidipine has a slightly longer half‑life and may produce a smoother 24‑hour blood pressure profile, whereas amlodipine is more widely used and has an extensive safety record. Choice between them depends on individual patient response, tolerability, and prescriber preference.
How should Lacydyna be stored?+
Lacydyna should be stored at ambient temperature, below 25 °C. Keep the tablets in the original container, protect them from moisture and direct light, and ensure the packaging remains tightly closed until use. Do not store in a refrigerator or freezer unless specifically instructed by the manufacturer.
How is Lacydyna administered?+
Lacydyna is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water. Patients should follow the dosing schedule provided by their healthcare professional and avoid crushing or chewing the tablet unless instructed otherwise.
What are the most serious risks associated with Lacydyna?+
Serious adverse events, although rare, include severe hypotension, myocardial infarction, angina, hepatic dysfunction, severe allergic reactions such as anaphylaxis, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms like faintness, chest pain, unusual fatigue, jaundice, rash, or irregular heartbeats while taking Lacydyna.
Who should not use Lacydyna?+
Lacydyna is contraindicated in patients with known hypersensitivity to lacidipine or any component of the formulation, in those with severe hypotension, cardiogenic shock, or unstable angina. Caution is also advised for individuals with significant hepatic impairment, as drug metabolism may be affected. Pregnant or nursing women should only use it when clearly indicated by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Lacidipine
Route
Oral Use
Manufacturer
Holsten Pharma Gmbh
Origin
EU

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