Lacipil

Lacidipine, the active ingredient in Lacipil, is a calcium channel blocker presented as a tablet for oral use. It is prescribed to lower high blood pressure in adult patients and helps reduce the risk of cardiovascular events.

GNH USA supplies Lacipil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lacidipine is a calcium channel blocker used primarily in the management of high blood pressure.

Hypertension: reduces elevated blood pressure and helps prevent cardiovascular complications.

Adverse reactions may occur with any antihypertensive therapy.

Common Side Effects: - Headache: mild to moderate intensity. - Flushing: transient warmth and redness of the skin. - Peripheral edema: swelling of the ankles or feet. - Dizziness or light‑headedness, especially after standing.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure requiring medical attention. - Myocardial infarction: rare occurrence of heart attack. - Hepatic dysfunction: abnormal liver enzyme elevations. - Allergic reactions: rash, itching, or urticaria. - Angioedema: swelling of the face, lips, or throat that may compromise breathing.

Patients should be monitored for safety and appropriate use. - Blood pressure monitoring: check regularly to ensure therapeutic effect. - Avoid abrupt discontinuation: taper under medical supervision to prevent rebound hypertension. - Hepatic impairment: use with caution and consider dose adjustment. - Concomitant antihypertensives: assess for additive hypotensive effects. - Store at room temperature: keep in the original pack, protect from moisture.

Lacidipine may interact with several drug classes.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase lacidipine plasma levels. - Grapefruit juice: can markedly raise drug concentration.

Moderate Interactions (Monitor Closely):\n- Non‑dihydropyridine calcium channel blockers: additive blood pressure lowering. - Diuretics: may enhance antihypertensive effect. - Beta‑blockers: monitor for excessive bradycardia or hypotension.