Europe — EMA
Iodure (131i) De Sodium Pour Therapie Curiumpharma (Sodium Iodide (131i))
GNH USA supplies Iodure (131i) De Sodium Pour Therapie Curiumpharma (Sodium Iodide 131I), a radioactive iodine for thyroid cancer and hyperthyroidism.
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What is Sodium Iodide (131i)?
Sodium Iodide (131I), the active ingredient in Iodure (131i) De Sodium Pour Therapie Curiumpharma, is a radioactive iodine presented as an oral radiopharmaceutical for oral use. It is employed in the treatment of thyroid cancer and hyperthyroidism in adult patients.
GNH USA supplies Iodure (131i) De Sodium Pour Therapie Curiumpharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.
What is Sodium Iodide (131i) used for?
Iodure (Sodium Iodide 131I) is a radioactive iodine used in therapeutic protocols targeting thyroid tissue. - Thyroid cancer: delivers targeted radiation to destroy malignant thyroid cells and reduce tumor burden. - Hyperthyroidism: ablates overactive thyroid tissue to restore normal hormone production. - Pre‑surgical thyroid ablation: reduces gland size and activity before thyroidectomy, facilitating safer surgery.
What are the side effects of Sodium Iodide (131i)?
Iodure (Sodium Iodide 131I) may cause a range of adverse reactions following oral administration.
Common Side Effects: - Nausea or vomiting: transient gastrointestinal upset after dosing. - Neck discomfort or pain: irritation of thyroid tissue. - Salivary gland swelling: temporary enlargement and tenderness. - Dry mouth or altered taste: reduced salivary flow.
Serious or Rare Side Effects: - Bone marrow suppression: decreased blood cell counts requiring monitoring. - Severe hypothyroidism: excessive loss of thyroid function. - Radiation thyroiditis: painful inflammation of the gland. - Allergic reaction: rash, itching, or anaphylaxis in rare cases.
What precautions apply to Sodium Iodide (131i)?
Prior to prescribing Iodure (Sodium Iodide 131I), clinicians should consider several safety measures. - Thyroid function assessment: confirm diagnosis and baseline hormone levels. - Pregnancy evaluation: avoid use in pregnant individuals unless benefits outweigh risks. - Concomitant medication review: identify agents that may interfere with iodine uptake. - Hematologic monitoring: check blood counts before and after therapy. - Radiation safety counseling: educate patients on post‑treatment precautions. - Store at ambient temperature: keep in original packaging, protect from moisture and light.
What does Sodium Iodide (131i) interact with?
Iodure (Sodium Iodide 131I) can interact with other medicines that affect thyroid function or bone marrow.
Major Interactions (Avoid): - Antithyroid drugs (e.g., propylthiouracil, methimazole): reduce therapeutic uptake. - Lithium: may alter thyroid hormone dynamics and increase toxicity. - Amiodarone: interferes with iodine metabolism and uptake.
Moderate Interactions (Monitor Closely): - Levothyroxine: dose may need adjustment after ablation. - Chemotherapy agents: overlapping risk of bone marrow suppression. - Beta‑blockers: can mask symptoms of thyroid storm. - Corticosteroids: may affect inflammatory response post‑treatment.


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