Europe — EMA
Intralipid (Soya Oil, Purified)
GNH USA supplies Intralipid (Soya Oil), a intravenous lipid emulsion for parenteral nutrition and essential fatty acid deficiency.
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What is Soya Oil, Purified?
Soya Oil, the active ingredient in Intralipid, is a intravenous lipid emulsion presented as a sterile emulsion for intravenous use. It provides calories and essential fatty acids for patients receiving parenteral nutrition, including those who cannot tolerate enteral feeding. GNH USA supplies Intralipid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.
What is Soya Oil, Purified used for?
Intralipid is used in the management of nutritional support and essential fatty acid deficiency in patients requiring parenteral feeding. - Parenteral nutrition in patients unable to receive enteral feeding: supplies calories and essential fatty acids to maintain energy balance. - Prevention of essential fatty acid deficiency: delivers linoleic and linolenic acids needed for cell membrane integrity. - Critical care caloric support: provides an immediate source of energy for critically ill patients on total parenteral nutrition.
What are the side effects of Soya Oil, Purified?
Intralipid may be associated with a range of adverse reactions.
Common Side Effects: - Hypertriglyceridemia: elevated serum triglyceride levels during therapy. - Fever or chills: transient temperature rise after infusion. - Nausea or vomiting: gastrointestinal discomfort. - Headache: mild to moderate intensity. - Injection site reactions: erythema or discomfort.
Serious or Rare Side Effects: - Fat overload syndrome: severe metabolic disturbance from excessive lipid load. - Pancreatitis: inflammation of the pancreas related to high triglyceride levels. - Anaphylaxis or severe allergic reaction: rapid onset respiratory or cardiovascular compromise. - Pulmonary embolism: rare embolic events from lipid particles. - Hepatic dysfunction: abnormal liver enzymes or steatosis.
What precautions apply to Soya Oil, Purified?
Prior to initiating Intralipid therapy, clinicians should consider several safety measures. - Monitor triglyceride levels: check serum triglycerides regularly to avoid hyperlipidemia. - Assess infection risk: avoid use in patients with uncontrolled sepsis. - Evaluate liver function: monitor hepatic enzymes during prolonged therapy. - Check for soy or egg phospholipid allergy: contraindicated in known hypersensitivity. - Use caution in pancreatitis history: consider alternative nutrition strategies. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.
What does Soya Oil, Purified interact with?
Intralipid can interact with other medications and nutritional products, requiring careful management.
Major Interactions (Avoid): - Concurrent propofol infusion: combined lipid load may cause fat overload. - Co‑administration with other lipid‑containing parenterals: risk of cumulative hypertriglyceridemia. - Use with fibrates: may exacerbate triglyceride elevation.
Moderate Interactions (Monitor Closely): - Heparin therapy: may alter triglyceride metabolism. - Corticosteroids: can increase serum triglyceride concentrations. - Dextrose‑containing total parenteral nutrition: monitor glucose and lipid balance.



