GNH USA

Europe — EMA

Infanrix-Ipv

GNH USA supplies Infanrix-Ipv (Pertussis Toxoid, Pertactin), a preventive vaccine for the prevention of pertussis (whooping cough).

Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid

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What is Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid?

Pertussis Toxoid, Pertactin, the active ingredient in Infanrix-Ipv, is a vaccine presented as a vaccine formulation for intramuscular use. It prevents pertussis (whooping cough) in infants and children.\n\nGNH India supplies Infanrix-Ipv as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and health‑care providers worldwide, ensuring quality‑controlled distribution and regulatory compliance.

What is Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid used for?

Infanrix-Ipv is a pertussis vaccine used to protect against Bordetella pertussis infection.\n\n- Pertussis (whooping cough): provides active immunity that reduces the risk of infection and severe disease in infants and children.\n- Infant immunisation schedule: contributes to the recommended primary series for early childhood protection.\n- Community health programs: supports herd immunity to lower overall pertussis transmission in the population.

What are the side effects of Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid?

Common Side Effects:\n- Injection site pain: mild to moderate discomfort at the injection site.\n- Redness or swelling: localized erythema or edema.\n- Fever: low‑grade temperature rise within 24‑48 hours.\n- Irritability or fussiness: especially in infants.\n- Loss of appetite: temporary decrease in feeding.\n\nSerious or Rare Side Effects:\n- Anaphylaxis: severe allergic reaction requiring immediate medical attention.\n- Seizures: rare neurologic events post‑vaccination.\n- High fever: temperature above 40°C that persists.\n- Prolonged crying: excessive crying lasting more than three hours.\n- Hypotonic‑hyporesponsive episode: transient loss of muscle tone in infants.

What precautions apply to Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid?

Infanrix-Ipv should be administered only after evaluating the individual's health status.\n\n- Allergy screening: avoid in persons with known hypersensitivity to any vaccine component.\n- Acute illness: postpone vaccination if the patient has a moderate or severe febrile illness.\n- Immunocompromised patients: assess risk‑benefit, as response may be reduced.\n- Concomitant vaccines: follow recommended intervals when co‑administering with live vaccines.\n- Storage: Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid interact with?

Vaccination with Infanrix-Ipv may be influenced by other medical products.\n\nMajor Interactions (Avoid):\n- Live attenuated vaccines: avoid administration within four weeks before or after Infanrix-Ipv.\n- Immunoglobulin therapy: concurrent use may diminish vaccine‑induced immunity.\n\nModerate Interactions (Monitor Closely):\n- Antipyretics before vaccination: may blunt antibody response; use only after vaccination if needed.\n- Systemic corticosteroids: may reduce immunogenicity, monitor antibody levels.\n- Blood products: transfusions within two weeks may interfere with vaccine effectiveness.

Frequently asked questions

What is Infanrix-Ipv used for?+
Infanrix-Ipv is a preventive vaccine indicated for the immunisation of infants and children against pertussis, also known as whooping cough. It helps the immune system develop protection by exposing it to pertussis toxoid and pertactin antigens, reducing the risk of infection and severe disease.
How does the pertussis toxoid and pertactin in Infanrix-Ipv work?+
The pertussis toxoid and pertactin antigens are adsorbed onto aluminium hydroxide, which acts as an adjuvant. After intramuscular injection, these antigens are taken up by antigen‑presenting cells, stimulating B‑cell and T‑cell responses that generate specific antibodies against Bordetella pertussis, providing protective immunity.
What is the usual dose of Infanrix-Ipv?+
The dosage and schedule of Infanrix-Ipv are determined by the prescribing healthcare professional based on national immunisation guidelines and the patient’s age. The prescriber will decide the appropriate volume and timing for each dose.
Is Infanrix-Ipv safe to use during pregnancy or breastfeeding?+
Infanrix-Ipv is generally not administered to pregnant women; instead, pertussis vaccination is recommended for pregnant women using a specific formulation (Tdap). Breastfeeding mothers may receive the vaccine if indicated, but they should consult their healthcare provider for personalized advice.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid
Route
Intramuscular Use
Manufacturer
Glaxosmithkline Biologicals S.A.
Origin
EU

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