GNH USA

Europe — EMA

Infanrix Polio

GNH USA supplies Infanrix Polio (Pertussis Toxoid), a vaccine for prevention of diphtheria, tetanus, pertussis and poliomyelitis.

Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid

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What is Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid?

Pertussis Toxoid Adsorbed on Aluminium Hydroxide and Pertussis Pertactin Adsorbed on Aluminium Hydroxide, the active ingredients in Infanrix Polio, are vaccine components presented as a combination diphtheria, tetanus, pertussis and poliomyelitis vaccine for intramuscular use. They stimulate active immunity against diphtheria toxin, tetanus toxin, pertussis antigens, and poliovirus, helping prevent these infections in infants and children.

GNH USA supplies Infanrix Polio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid used for?

Infanrix Polio is a combination vaccine that targets bacterial toxins and poliovirus to prevent several childhood diseases. - Diphtheria: provides active immunity to prevent diphtheria infection. - Tetanus: induces antibodies that protect against tetanus toxin. - Pertussis (whooping cough): stimulates protection against Bordetella pertussis. - Poliomyelitis: generates immunity that blocks poliovirus replication.

What are the side effects of Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid?

Common Side Effects: - Injection site pain, redness or swelling. - Low‑grade fever. - Irritability or fussiness in infants. - Decreased appetite. - Mild rash at the injection site.

Serious or Rare Side Effects: - Anaphylactic reaction (severe allergic response). - Seizures or high‑grade fever. - Prolonged crying episodes. - Hypotonic‑hyporesponsive episodes. - Encephalopathy or neurologic complications. - Severe local inflammation requiring medical attention.

What precautions apply to Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid?

Infanrix Polio should be administered according to national immunisation schedules and under professional supervision. - Age: give only to infants and children as recommended by health authorities. - Allergy: avoid if the patient has a known hypersensitivity to any vaccine component. - Medical conditions: consult a healthcare provider for children with severe immunodeficiency. - Concurrent vaccines: can be co‑administered with other routine vaccines following guideline timing. - Pregnancy: not indicated for pregnant women; discuss risks with a clinician. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid interact with?

Infanrix Polio may interact with other agents that affect immune response. Major Interactions (Avoid): - Live attenuated vaccines: avoid simultaneous administration. - Immunoglobulins: may reduce vaccine efficacy if given within two weeks. - Blood products: can interfere with immune response if administered shortly before or after vaccination. Moderate Interactions (Monitor Closely): - Antipyretics: may mask post‑vaccination fever. - High‑dose corticosteroids: could diminish antibody production. - Other vaccines: schedule spacing as per immunisation guidelines.

Frequently asked questions

What is Infanrix Polio used for?+
Infanrix Polio is a combination vaccine used to prevent four serious infectious diseases—diphtheria, tetanus, pertussis (whooping cough) and poliomyelitis—in infants and young children as part of routine immunisation programmes.
How does the active ingredient in Infanrix Polio work?+
The vaccine contains inactivated diphtheria and tetanus toxoids, pertussis antigens (toxoid and pertactin) bound to aluminium hydroxide, and inactivated poliovirus. These components stimulate the immune system to produce specific antibodies and memory cells that neutralise the toxins and block poliovirus infection.
What is the usual dose of Infanrix Polio?+
The dose and schedule are determined by the prescribing healthcare professional based on national immunisation guidelines. Typically, the vaccine is given as a series of intramuscular injections at specific ages, but the exact regimen must be set by the clinician.
Is Infanrix Polio safe during pregnancy or breastfeeding?+
Infanrix Polio is not recommended for use in pregnant women because safety data are limited. Women who are breastfeeding should consult their healthcare provider, as the vaccine is generally intended for infants rather than for maternal administration.
How do I order Infanrix Polio from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and any necessary import documentation.
How does Infanrix Polio compare with other DTP‑Polio vaccines?+
Infanrix Polio is a licensed, EU‑approved combination vaccine that includes aluminium‑hydroxide‑adsorbed pertussis antigens, offering comparable immunogenicity to other DTP‑Polio products such as Daptacel or Pentacel. Differences may lie in specific antigen formulations, adjuvant content and regulatory approvals, but all aim to provide protection against the same four diseases.
What are the storage and handling requirements for Infanrix Polio?+
The vaccine must be stored at 2‑8 °C, protected from light, and kept in its original packaging. It should never be frozen or shaken. If temperature excursions occur, discard the product according to the manufacturer’s guidance.
How is Infanrix Polio administered?+
Infanrix Polio is given by intramuscular injection, usually into the anterolateral thigh of infants or the deltoid muscle of older children, following the recommended immunisation schedule. Administration should be performed by a qualified healthcare professional.
What are the most serious risks associated with Infanrix Polio?+
The most serious adverse events include severe allergic reactions (anaphylaxis), seizures, high‑grade fever, and rare neurologic complications such as encephalopathy. Any signs of a serious reaction require immediate medical attention.
Who should not receive Infanrix Polio?+
Infanrix Polio is contraindicated in individuals with a known severe allergy to any vaccine component, including aluminium salts, or in those who have experienced a previous severe reaction to a DTP‑Polio vaccine. Children with severe immunodeficiency should receive the vaccine only after specialist evaluation.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Pertussis Toxoid Adsorbed On Aluminium Hydroxide, Pertussis Pertactin Adsorbed On Aluminium Hydroxid
Route
Intramuscular Use
Manufacturer
Glaxosmithkline Biologicals S.A.
Origin
EU

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