Europe — EMA
Glucose Proamp Laboratoire Aguettant
Glucose Proamp Laboratoire Aguettant is an EU‑marketed IV glucose solution used for hypoglycemia, parenteral nutrition, and fluid replacement.
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What is Glucose?
Glucose Proamp Laboratoire Aguettant is an intravenous solution whose sole active ingredient is glucose. It is supplied in a sterile liquid form for infusion and is marketed in the European Union. The product provides a source of carbohydrate that can be used to support cellular energy metabolism when administered directly into the bloodstream.
What is Glucose used for?
Glucose Proamp is indicated for situations where rapid provision of carbohydrate energy is required. It is commonly employed in clinical settings for the following purposes:
- Treatment of documented hypoglycemia in adults and children. - Component of parenteral nutrition regimens to supply calories. - Fluid replacement when combined with electrolytes. - Intra‑operative or peri‑operative glucose support. - Management of electrolyte disturbances associated with low blood glucose.
What are the side effects of Glucose?
Side effects of intravenous glucose solutions are generally related to the metabolic and local effects of the infusion.
Common: - Transient hyperglycemia or elevated blood glucose levels. - Local irritation or phlebitis at the infusion site. - Mild electrolyte shifts, particularly sodium and potassium. - Fluid overload when administered rapidly. - Nausea or abdominal discomfort.
Serious: - Severe hyperglycemia leading to osmotic diuresis. - Anaphylactic or severe allergic reaction. - Cardiac arrhythmias associated with rapid glucose shifts. - Hyperosmolar hyperglycemic state in susceptible patients. - Acute renal dysfunction secondary to volume overload.
What precautions apply to Glucose?
When using Glucose Proamp, clinicians should observe several safety measures to minimize risks. Important precautions include:
- Regular monitoring of blood glucose concentrations during and after infusion. - Adjusting infusion rates in patients with renal or hepatic impairment. - Using aseptic technique to prevent catheter‑related infections. - Exercising caution in pregnant or breastfeeding individuals, as safety data are limited. - Evaluating pediatric patients carefully, with dose individualized by weight. - Avoiding rapid bolus administration unless clinically indicated.
What does Glucose interact with?
Glucose Proamp may interact with other agents that affect blood glucose or electrolyte balance.
Avoid: - Concurrent high‑dose insulin or insulin analogues that could precipitate severe hypoglycemia. - Sulfonylureas or other oral hypoglycemic agents without appropriate glucose monitoring.
Use with caution: - Diuretics that may alter sodium and potassium levels. - Beta‑blockers, which can mask hypoglycemia symptoms. - Corticosteroids or catecholamines that raise blood glucose. - Potassium‑containing solutions, due to potential shifts in serum potassium. - Other intravenous carbohydrate solutions, to prevent excessive caloric load.



