Europe — EMA
Glucos Fresenius Kabi (Glucose)
Glucos Fresenius Kabi is an IV glucose solution for parenteral nutrition, hypoglycemia treatment, and fluid/electrolyte replacement in EU hospitals.
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What is Glucose?
Glucos Fresenius Kabi is an intravenous solution containing glucose as the active ingredient. It is supplied in a parenteral nutrition formulation without a disclosed strength, intended for intravenous administration. The product is marketed in the European Union and classified as a prescription (Rx) excipient used to provide carbohydrate energy in clinical settings.
What is Glucose used for?
Glucos Fresenius Kabi is employed when a rapid source of carbohydrate is required intravenously. It supports patients who cannot receive oral nutrition and helps maintain fluid and electrolyte balance.
- Treatment of hypoglycemia in acute care settings - Component of total parenteral nutrition (TPN) regimens - Fluid and electrolyte replacement during surgery or trauma - Support for critically ill patients requiring energy supplementation - Nutritional support for neonates and infants when enteral feeding is not possible
What are the side effects of Glucose?
Side effects of intravenous glucose solutions can vary in frequency and severity.
Common: - Hyperglycemia (elevated blood glucose levels) - Local irritation or phlebitis at the infusion site - Electrolyte disturbances, such as hyponatremia - Fluid overload, especially in patients with cardiac or renal impairment
Serious: - Severe hyperglycemia leading to diabetic ketoacidosis - Allergic reaction or anaphylaxis (rare) - Severe electrolyte imbalance causing cardiac arrhythmia - Pulmonary edema due to rapid volume expansion
What precautions apply to Glucose?
Clinicians should assess patient-specific factors before administering Glucos Fresenius Kabi. Proper monitoring and dosage adjustments are essential to minimize risks.
- Verify blood glucose levels prior to infusion and monitor during therapy - Adjust infusion rate in patients with renal or cardiac failure to avoid fluid overload - Use caution in diabetic patients or those with impaired glucose tolerance - Ensure compatibility with other intravenous solutions to prevent precipitation - Observe for signs of infection at the catheter site - Document any adverse reactions promptly
What does Glucose interact with?
Glucose solutions may interact with other medications or clinical conditions, influencing safety and efficacy.
Avoid: - Co-administration with high-dose insulin without appropriate monitoring, which can cause severe hypoglycemia - Simultaneous infusion of calcium-containing solutions that may precipitate with phosphate
Use with caution: - Concurrent use of diuretics, which may exacerbate electrolyte shifts - Administration alongside beta‑adrenergic agonists that can increase blood glucose levels - Use in patients receiving corticosteroids, which may raise glucose concentrations - Combination with other hypertonic solutions, requiring careful volume management



