GNH USA

Europe — EMA

Movicol®

GNH USA supplies Movicol (Macrogol 3350), a osmotic laxative for constipation, fecal impaction and bowel preparation. Request a quote for global supply.

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350

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What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Macrogol 3350, the active ingredient in Movicol, is an osmotic laxative presented as a 13.125 g per sachet powder for oral solution use. It treats constipation, fecal impaction and is used for bowel preparation in adults and children as directed by a healthcare professional.

GNH USA supplies Movicol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 used for?

Movicol is an osmotic laxative used to manage conditions affecting bowel transit.

- Constipation: softens stool and facilitates regular bowel movements. - Fecal impaction: helps relieve hardened stool accumulation. - Bowel preparation for diagnostic procedures: clears the intestinal tract before colonoscopy or imaging.

What are the side effects of Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Common side effects are generally mild and related to gastrointestinal tolerance.

Common Side Effects: - Abdominal bloating: sensation of fullness or swelling in the abdomen. - Flatulence: increased intestinal gas. - Nausea: feeling of queasiness. - Stomach cramps: intermittent abdominal pain. - Diarrhoea: loose, watery stools. - Thirst: increased desire for fluids.

Serious or Rare Side Effects: - Electrolyte imbalance: abnormal levels of sodium, potassium or chloride. - Severe dehydration: excessive loss of body water. - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Severe abdominal pain: persistent, intense discomfort. - Hypovolaemia: marked reduction in blood volume. - Anaphylaxis: life‑threatening systemic allergic response.

What precautions apply to Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350?

Before using Movicol, consider the following safety measures.

- Renal impairment: monitor fluid and electrolyte status closely. - Heart failure: use with caution due to potential fluid shifts. - Pregnancy: safety not established; consult a healthcare provider. - Elderly patients: increased risk of dehydration; ensure adequate fluid intake. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350 interact with?

Movicol may interact with other medicines; review the following categories.

Major Interactions (Avoid): - Lithium: increased risk of lithium toxicity due to altered renal clearance. - Diuretics: may exacerbate electrolyte disturbances.

Moderate Interactions (Monitor Closely): - Antacids containing magnesium or aluminium: may reduce laxative efficacy. - Other osmotic laxatives: additive effect can lead to dehydration. - ACE inhibitors: monitor potassium levels during combined use.

Frequently asked questions

What is Movicol used for?+
Movicol is indicated for the relief of constipation, the treatment of fecal impaction, and as a bowel‑cleansing agent before diagnostic procedures such as colonoscopy. It works by softening stool and promoting regular bowel movements in adults and children when prescribed.
How does Macrogol 3350 work?+
Macrogol 3350 is a high‑molecular‑weight polymer that draws water into the intestinal lumen by creating an osmotic gradient. The retained water softens the stool, while the added electrolytes help maintain fluid balance, resulting in increased bowel motility and easier passage of feces.
What is the usual dose of Movicol?+
The dose of Movicol is individualized by a prescriber based on the patient’s age, condition severity, and response to therapy. Healthcare professionals determine the number of sachets to dissolve in water and the frequency of administration for each specific case.
Is Movicol safe during pregnancy or breastfeeding?+
Safety data for Movicol in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before use.
How do I order Movicol from GNH USA?+
To order Movicol, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Movicol compare with other laxatives?+
Movicol belongs to the osmotic laxative class, which works by retaining water in the gut, whereas stimulant laxatives such as bisacodyl increase intestinal muscle contractions. Osmotic agents like Movicol are generally gentler and suitable for longer‑term use, while stimulants may cause cramping and are often reserved for occasional relief.
How should Movicol be stored and handled?+
Movicol sachets should be stored at ambient temperature, below 25 °C, in their original packaging to protect from moisture. Keep the product out of direct sunlight and away from heat sources. Do not use if the sachet is damaged or the powder appears discoloured.
How is Movicol administered?+
Each Movicol sachet is dissolved in a specified volume of water (usually 125 ml) and the solution is consumed immediately after mixing. The drink should be taken with additional fluids as advised by a healthcare professional to maintain adequate hydration.
What are the most serious risks to watch for when using Movicol?+
Serious risks include electrolyte imbalance, severe dehydration, and rare allergic reactions such as rash, swelling or anaphylaxis. Patients should seek medical attention promptly if they experience symptoms like rapid heartbeat, muscle weakness, severe abdominal pain, or signs of an allergic response.
Who should not use Movicol?+
Movicol should be avoided in individuals with known hypersensitivity to macrogol or any of its electrolytes, in patients with intestinal obstruction, perforation, or severe inflammatory bowel disease, and in those with uncontrolled heart failure or severe renal impairment unless closely monitored by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Route
Oral Use
Manufacturer
Norgine Nv/Sa
Origin
EU

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