GNH USA

USA — NDC

Protonix Delayed-Release 40 mg/1

GNH USA supplies Protonix 40 mg Tablet (Pantoprazole), a proton pump inhibitor for GERD and erosive esophagitis. Request a quote for global supply.

Pantoprazole Sodium
Protonix Delayed-Release
TABLET, DELAYED RELEASE
40 mg/1

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1
Pack/s

What is Pantoprazole Sodium?

Pantoprazole sodium, the active ingredient in Protonix Delayed-Release, is a proton pump inhibitor (PPI) presented as a 40 mg delayed-release tablet for oral use. It is used to treat conditions related to excess stomach acid, such as gastroesophageal reflux disease (GERD) and erosive esophagitis. GNH USA supplies Protonix Delayed-Release as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Protonix Delayed-Release is a widely recognized medication for managing acid-related gastrointestinal conditions. Its delayed-release formulation ensures that the active ingredient is released in the intestine, where it can effectively reduce stomach acid production.

What is Pantoprazole Sodium used for?

Protonix Delayed-Release is a proton pump inhibitor (PPI) used to treat conditions related to excess stomach acid. It is indicated for the following conditions:

- Gastroesophageal reflux disease (GERD): Reduces symptoms such as heartburn, difficulty swallowing, and persistent cough. - Erosive esophagitis: Helps heal acid damage to the esophagus and prevents further damage. - Zollinger-Ellison syndrome: Manages pathological gastric acid hypersecretion. - Prevention of NSAID-induced gastric ulcers: Protects the stomach lining from damage caused by nonsteroidal anti-inflammatory drugs (NSAIDs).

What are the side effects of Pantoprazole Sodium?

Protonix Delayed-Release may cause side effects, although not everyone experiences them. Common Side Effects: - Headache - Diarrhea - Nausea - Abdominal pain - Constipation - Gas

Serious or Rare Side Effects: - Symptoms of a low magnesium blood level (such as unusually fast/slow/irregular heartbeat, persistent muscle spasms, seizures) - Signs of lupus (such as rash on nose and cheeks, new or worsening joint pain) - Severe intestinal condition due to C. difficile bacteria (symptoms include persistent diarrhea, abdominal pain, fever, and blood/mucus in stool) - Vitamin B-12 deficiency (symptoms include unusual weakness, sore tongue, or numbness/tingling of the hands/feet) - Severe allergic reactions (symptoms include rash, itching/swelling, severe dizziness, trouble breathing).

What precautions apply to Pantoprazole Sodium?

Before taking Protonix Delayed-Release, it is important to consider certain precautions. Inform your doctor if you are allergic to pantoprazole or similar drugs. Tell your doctor about any medical conditions you have, especially liver disease or lupus. Some symptoms may indicate a more serious condition, so seek medical help immediately if you experience heartburn with lightheadedness, chest pain, or unexplained weight loss. Older adults may be more sensitive to the side effects of this drug. During pregnancy, use this medication only when clearly needed. Consult your doctor before breastfeeding. Store below 25°C: keep in the original pack, protect from moisture.

What does Pantoprazole Sodium interact with?

Protonix Delayed-Release may interact with other medications, altering their effectiveness or increasing the risk of side effects. Major Interactions (Avoid): - Methotrexate (especially high-dose treatment): Pantoprazole may increase the risk of methotrexate toxicity. - Ampicillin, atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, certain azole antifungals (itraconazole, ketoconazole, posaconazole): Pantoprazole may reduce the absorption of these drugs.

Moderate Interactions (Monitor Closely): - Other medications that require stomach acid for proper absorption: Pantoprazole may affect their effectiveness. - Antacids: May be taken along with Protonix Delayed-Release but should be taken at least 30 minutes before sucralfate.

Frequently asked questions

What is Protonix Delayed-Release used for?+
Protonix Delayed-Release is used to treat conditions related to excess stomach acid, such as gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, and to prevent NSAID-induced gastric ulcers. It works by reducing the amount of acid produced in the stomach, alleviating symptoms like heartburn, difficulty swallowing, and persistent cough.
How does pantoprazole sodium work?+
Pantoprazole sodium, the active ingredient in Protonix Delayed-Release, works by irreversibly inhibiting the H+/K+ ATPase (gastric proton pump) in the parietal cells of the stomach. This inhibition suppresses gastric acid secretion, reducing the amount of acid produced in the stomach and alleviating symptoms associated with excess acid.
What is the usual dose of Protonix Delayed-Release?+
The usual dose of Protonix Delayed-Release is determined by a healthcare professional based on the patient's medical condition and response to treatment. It is typically taken once daily, with or without food. The tablets should be swallowed whole and not crushed or chewed.
Is Protonix Delayed-Release safe during pregnancy or breastfeeding?+
During pregnancy, Protonix Delayed-Release should be used only when clearly needed. Discuss the risks and benefits with your doctor. This medication passes into breast milk, so consult your doctor before breastfeeding.
How do I order Protonix Delayed-Release from GNH USA?+
To order Protonix Delayed-Release from GNH USA, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.
How does Protonix Delayed-Release compare to other proton pump inhibitors?+
Protonix Delayed-Release is one of several proton pump inhibitors (PPIs) available for treating acid-related gastrointestinal conditions. It is similar to other PPIs like omeprazole and lansoprazole in its mechanism of action and indications. The choice of PPI may depend on individual patient factors, such as effectiveness, side effects, and cost.
How should Protonix Delayed-Release be stored and handled?+
Protonix Delayed-Release should be stored below 25°C, kept in the original pack, and protected from moisture. Ensure the medication is stored in a cool, dry place away from direct sunlight and out of reach of children.
How is Protonix Delayed-Release administered?+
Protonix Delayed-Release is taken orally, usually once daily, with or without food. The tablets should be swallowed whole and not crushed or chewed. If the granules are used, they should be taken 30 minutes before a meal and mixed with applesauce or apple juice.
What are the most serious risks to watch for with Protonix Delayed-Release?+
The most serious risks to watch for with Protonix Delayed-Release include symptoms of a low magnesium blood level, signs of lupus, severe intestinal condition due to C. difficile bacteria, vitamin B-12 deficiency, and severe allergic reactions. Seek medical help immediately if you experience any of these symptoms.
Who should not use Protonix Delayed-Release?+
Protonix Delayed-Release should not be used by individuals who are allergic to pantoprazole or similar drugs. Patients with certain medical conditions, such as liver disease or lupus, should consult their doctor before using this medication. Always inform your healthcare professional about any allergies or medical conditions you have.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Pantoprazole Sodium
Brand
Protonix Delayed-Release
Strength
40 mg/1
Form
TABLET, DELAYED RELEASE
Route
ORAL
Pack size
90 TABLET, DELAYED RELEASE in 1 BOTTLE (0008-0841-81)
Manufacturer
Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.
Origin
USA

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