Paramax Extra (Paracetamol, Caffeine)

Paracetamol, the active ingredient in Paramax Extra, is an Analgesic/Antipyretic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children.

GNH USA supplies Paramax Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Paramax Extra combines paracetamol and caffeine, acting on pain‑related pathways and central fatigue. - Headache: provides relief of tension‑type and migraine‑associated pain. - Fever: reduces elevated body temperature in infectious or inflammatory states. - Minor musculoskeletal pain: eases discomfort from back strain, sprains and arthritic flares. - Post‑operative discomfort: supports analgesia after minor surgical procedures. - Fatigue‑related headache: alleviates headache linked to caffeine withdrawal or low energy.

Paracetamol/caffeine tablets are generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset may be reported. - Insomnia: difficulty falling or staying asleep. - Restlessness: feeling of increased nervous energy. - Gastric discomfort: mild abdominal pain or heartburn. - Tremor: slight shaking of hands. - Palpitations: sensation of rapid heartbeat.

Serious or Rare Side Effects: - Hepatotoxicity: liver injury, especially with overdose or chronic use. - Allergic reaction: rash, itching, swelling or anaphylaxis. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Cardiovascular events: arrhythmia or hypertension exacerbation. - Bleeding tendency: prolonged bruising or abnormal bleeding. - Hypersensitivity: bronchospasm or airway swelling.

When using Paramax Extra, consider the following safety measures: - Dose limitation: do not exceed the maximum daily amount of paracetamol. - Liver health: avoid use in patients with known hepatic impairment. - Pregnancy: consult a healthcare professional before use during pregnancy. - Drug interactions: review concomitant medications for potential additive effects. - Age restrictions: not recommended for children under a specified age without medical advice. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Paramax Extra may interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Warfarin: increased risk of bleeding due to enhanced anticoagulant effect. - Rifampicin: reduced paracetamol plasma levels, diminishing analgesic effect. - Phenobarbital: accelerated metabolism of paracetamol, lowering efficacy.

Moderate Interactions (Monitor Closely): - Antidepressants (SSRIs, SNRIs): potential for increased serotonin syndrome risk. - Diuretics: heightened caffeine‑induced diuresis may affect fluid balance. - Beta‑blockers: possible augmentation of caffeine‑induced tachycardia.