Europe — EMA
Paramax Extra (Paracetamol, Caffeine)
GNH USA supplies Paramax Extra (Paracetamol, Caffeine), a Analgesic/Antipyretic and Central Nervous System Stimulant for pain and fever.
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What is Paracetamol, Caffeine?
Paracetamol, the active ingredient in Paramax Extra, is an Analgesic/Antipyretic and Central Nervous System Stimulant presented as a tablet for oral use. It treats mild to moderate pain and fever in adults and children when appropriate dosing is applied.
GNH USA supplies Paramax Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol, Caffeine used for?
Paramax Extra combines paracetamol and caffeine, acting on pain‑related pathways and central fatigue to provide relief in several common conditions. - Headache: reduces intensity and improves alertness during episodic tension‑type headaches. - Fever: lowers elevated body temperature associated with viral or bacterial infections. - Minor musculoskeletal pain: eases discomfort from strains, sprains and low‑back tension. - Migraine (adjunct): enhances the analgesic effect of paracetamol in acute migraine attacks. - Dental pain: provides short‑term relief following dental procedures.
What are the side effects of Paracetamol, Caffeine?
Paracetamol/caffeine is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset reported in some users. - Insomnia: difficulty falling asleep, especially when taken later in the day. - Restlessness: feeling of increased nervous energy. - Gastro‑intestinal discomfort: mild abdominal pain or heartburn. - Headache: paradoxical worsening of head pain in rare cases.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or anaphylaxis. - Hepatotoxicity: liver injury from excessive paracetamol exposure. - Cardiac arrhythmia: irregular heartbeat linked to high caffeine intake. - Seizures: rare occurrence, particularly in overdose situations.
What precautions apply to Paracetamol, Caffeine?
When using Paramax Extra, consider the following safety measures: - Dose limitation: do not exceed the maximum daily amount of paracetamol. - Liver health: avoid use in patients with severe hepatic impairment. - Caffeine sensitivity: caution in individuals prone to anxiety, insomnia or tachycardia. - Pregnancy and lactation: consult a healthcare professional before use. - Drug interactions: review concomitant medications for potential additive effects. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol, Caffeine interact with?
Paramax Extra may interact with several medicines; monitoring is advised.
Major Interactions (Avoid): - Warfarin: increased risk of bleeding due to altered metabolism. - Isoniazid: heightened risk of liver toxicity when combined with paracetamol. - Monoamine oxidase inhibitors (MAOIs): potential for hypertensive crisis with caffeine.
Moderate Interactions (Monitor Closely): - Anticonvulsants (e.g., carbamazepine): may reduce paracetamol effectiveness. - Beta‑blockers: caffeine can diminish blood‑pressure‑lowering effects. - Diuretics: may increase caffeine‑related diuresis and electrolyte loss.



