Paralgin Forte (Codeine Phosphate Sesquihydrate, Paracetamol)

Codeine Phosphate Sesquihydrate, the active ingredient in Paralgin Forte, is an opioid analgesic presented as a combination tablet for oral use. It relieves moderate to severe pain and reduces fever in adult patients. GNH USA supplies Paralgin Forte as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH USA supplies Paralgin Forte as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paralgin Forte combines a weak opioid with a non‑opioid analgesic, acting on pain pathways to provide relief in several common conditions.

- Headache: reduces pain intensity and associated discomfort. - Dental pain: alleviates postoperative or inflammatory dental discomfort. - Musculoskeletal pain: eases aches and strains of muscles and joints. - Fever: lowers elevated body temperature in acute febrile states. - Minor injury pain: provides symptomatic relief after cuts, bruises or sprains.

Paralgin Forte may cause a range of adverse reactions, most of which are dose‑dependent and reversible.

Common Side Effects: - Nausea or vomiting - Constipation - Drowsiness or mild sedation - Dizziness - Dry mouth - Sweating

Serious or Rare Side Effects: - Respiratory depression - Severe allergic reactions (anaphylaxis, skin rash) - Hepatotoxicity with excessive paracetamol exposure - Opioid dependence or withdrawal syndrome - Low blood pressure (hypotension) - Seizures (rare)

When using Paralgin Forte, consider the following safety measures:

- Assess pain severity: ensure the product matches the intensity of the patient's pain. - Review medical history: check for respiratory disorders, liver disease, or opioid sensitivity. - Avoid alcohol: concurrent use can increase sedation and respiratory risk. - Monitor for dependence: limit duration of use to the shortest effective period. - Pregnancy and lactation: use only if clearly needed and prescribed by a healthcare professional. - Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture.

Paralgin Forte can interact with several other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid): - CNS depressants: may enhance sedation and respiratory depression. - MAO inhibitors: can precipitate severe opioid reactions. - Strong CYP2D6 inhibitors (e.g., fluoxetine) reduce conversion of codeine to morphine.

Moderate Interactions (Monitor Closely): - Alcohol: increases risk of drowsiness and gastrointestinal upset. - Anticoagulants (warfarin): may increase bleeding risk with high‑dose paracetamol.\n