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What is Paracetamol?
Paracetamol, the active ingredient in Paralen 100, is an analgesic presented as a 100 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children. GNH USA supplies Paralen 100 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Paralen 100 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Paralen 100 contains paracetamol, an analgesic that acts on the body's pain‑and‑temperature pathways. - Headache: provides relief from mild to moderate tension‑type or migraine‑associated pain. - Fever: reduces elevated body temperature in febrile conditions. - Musculoskeletal pain: eases discomfort from strains, sprains and low‑back pain. - Dental pain: alleviates pain following dental procedures or toothache. - Osteoarthritis: helps manage chronic joint pain in mild cases.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset may be experienced. - Rash: occasional skin redness or itching. - Elevated liver enzymes: transient increase detected in blood tests.
Serious or Rare Side Effects: - Hepatotoxicity: risk of liver injury with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction. - Anaphylaxis: extremely rare allergic response requiring immediate medical attention. - Blood disorders: rare cases of thrombocytopenia or neutropenia.
What precautions apply to Paracetamol?
When using Paralen 100, consider the following safety measures: - Dose limitation: do not exceed the recommended daily maximum of 4 g for adults. - Alcohol use: avoid concurrent excessive alcohol consumption, which can increase liver risk. - Liver disease: patients with existing hepatic impairment should use only under medical supervision. - Pregnancy: consult a healthcare professional before use during pregnancy or lactation. - Drug interactions: review all concurrent medications with a clinician. - Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with several medicines; monitoring is advised.
Major Interactions (Avoid): - Warfarin: may enhance anticoagulant effect and increase bleeding risk.
Moderate Interactions (Monitor Closely): - Isoniazid: can increase risk of liver toxicity. - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol clearance. - Rifampicin: may lower plasma concentrations of paracetamol. - HIV protease inhibitors: potential for altered metabolism. - High‑dose vitamin C: may affect renal excretion of paracetamet
